Evidence map›Paper›PMID 38053451›Full record

ReviewChemical communications (Cambridge, England)2023

Sample transformation in online separations: how chemical conversion advances analytical technology.

Annika A M van der Zon, Joshka Verduin, Rick S van den Hurk, Andrea F G Gargano, Bob W J Pirok

Abstract readReview
In one paragraph

Review in Chemical communications (Cambridge, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Nephelometry as a simple tool to monitor the disassembly of polymeric nanoparticles.Analytical methods : advancing methods and applications · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annika A M van der ZonUniversity of Amsterdam, van't Hoff Institute for Molecular Sciences, Analytical Chemistry Group, Science Park 904, 1098 XH Amsterdam, The Netherlands. B.W.J.Pirok@uva.nl.ORCID http://orcid.org/0009-0001-9113-3014
Joshka VerduinCentre of Analytical Sciences Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5862-6036
Rick S van den HurkUniversity of Amsterdam, van't Hoff Institute for Molecular Sciences, Analytical Chemistry Group, Science Park 904, 1098 XH Amsterdam, The Netherlands. B.W.J.Pirok@uva.nl.ORCID http://orcid.org/0000-0002-1334-0480
Andrea F G GarganoUniversity of Amsterdam, van't Hoff Institute for Molecular Sciences, Analytical Chemistry Group, Science Park 904, 1098 XH Amsterdam, The Netherlands. B.W.J.Pirok@uva.nl.
Bob W J PirokUniversity of Amsterdam, van't Hoff Institute for Molecular Sciences, Analytical Chemistry Group, Science Park 904, 1098 XH Amsterdam, The Netherlands. B.W.J.Pirok@uva.nl.ORCID http://orcid.org/0000-0002-4558-3778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the advent of modern analytical technology has allowed scientists to determine the complexity of mixtures, it also spurred the demand to understand these sophisticated mixtures better. Chemical transformation can be used to provide insights into properties of complex samples such as degradation pathways or molecular heterogeneity that are otherwise unaccessible. In this article, we explore how sample transformation is exploited across different application fields to empower analytical methods. Transformation mechanisms include molecular-weight reduction, controlled degradation, and derivatization. Both offline and online transformation methods have been explored. The covered studies show that sample transformation facilitates faster reactions (

Identifiers

PMID38053451
PMCPMC10729587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.