Evidence map›Paper›PMID 38053138›Full record

ArticleBMC veterinary research2023

Antimicrobial resistance in E. Coli of animal origin and discovery of a novel ICE mobile element in Northeast China.

Dao Mi Zhu, Qiang Ding, Peng Hui Li, Yong Liang Wang, Ya Zhuo Li, Xuan Yu Li, Gong Mei Li, Hong Xia Ma, Ling Cong Kong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Detection of drug resistance inFrontiers in veterinary science · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dao Mi ZhuCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Qiang DingCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Peng Hui LiCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Yong Liang WangCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Ya Zhuo LiCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Xuan Yu LiCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Gong Mei LiCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China.
Hong Xia MaCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China. hongxia0731001@163.com.
Ling Cong KongCollege of Animal Science and Technology, Jilin Agricultural University, Xincheng Street#2888, Changchun, 130118, P.R. China. lingcong@jlau.edu.cn.

Funding

Natural Science Foundation of Jilin Province 20210202033NCNatural Science Foundation of Jilin Province 20220202060NCNatural Science Foundation of Jilin Province YDJ202203CGZH050
6 · The paper itself

Abstract

backgroundMultidrug resistance in Enterobacteriaceae including resistance to quinolones is rising worldwide. The development of resistance may lead to the emergence of new transmission mechanisms. In this study, the collection of different E. coli was performed from animals and subjected to subsequent procedures including pulsed-field gel electrophoresis, micro-broth dilution method, polymerase chain reaction. Whole genome sequencing of E. coli C3 was performed to detect the affinity, antimicrobial resistance and major carriers of the isolates.

resultsA total of 66 E. coli were isolated and their antibiotic resistance genes, frequency of horizontal transfer and genetic environment of E. coli C3 were determined. The results showed there were both different and same types in PFGE typing, indicating clonal transmission of E. coli among different animals. The detection of antimicrobial resistance and major antibiotic resistance genes and the plasmid transfer results showed that strains from different sources had high levels of resistance to commonly used clinical antibiotics and could be spread horizontally. Whole-genome sequencing discovered a novel ICE mobile element.

conclusionIn summary, the antimicrobial resistance of E. coli in northeast China is a serious issue and there is a risk of antimicrobial resistance transmission. Meanwhile, a novel ICE mobile element appeared in the process of antimicrobial resistance formation.

Indexed as

Escherichia coliEscherichia coli InfectionsAnimalsAnti-Bacterial Agentsbeta-LactamasesChinaDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldEnterobacteriaceaeMicrobial Sensitivity TestsPlasmidsAnti-Bacterial Agentsbeta-LactamasesAntimicrobial resistanceAntimicrobial resistance genesE. ColiNovel ICESpread of antimicrobial resistance

Identifiers

PMID38053138
PMCPMC10696688

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.