Evidence map›Paper›PMID 38053082›Full record

Trial reportBMC gastroenterology2023

3 L split-dose polyethylene glycol is superior to 2 L polyethylene glycol in colonoscopic bowel preparation in relatively high-BMI (≥ 24 kg/m

Hailin Yan, Hongyu Huang, Dailan Yang, Zonghua Chen, Chao Liu, Zhong Huang, Rui Zhao, Jing Shan, Li Yang, Jinlin Yang and 1 more

Open access · goldAbstract readRandomized Controlled TrialMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Hailin Yan *Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Hongyu Huang *Department of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Dailan YangDepartment of Gastroenterology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Zonghua ChenDepartment of Gastroenterology, Yibin Second People's Hospital, Yibin, 644000, Sichuan, China.
Chao LiuDepartment of Gastroenterology, Hospital of the Office of the Tibet Autonomous Region People's Government in Chengdu, Chengdu, 610041, Sichuan, China.
Zhong HuangDivision of Gastroenterology, Zigong First People's Hospital, Zigong, 643000, Sichuan, China.
Rui ZhaoSichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, Chengdu, 610041, Sichuan, China.
Jing ShanDepartment of Gastroenterology, The 3rd People's Hospital of Chengdu, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.
Li YangDepartment of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Jinlin YangDepartment of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. yangjinlin@wchscu.cn.
Kai DengDepartment of Gastroenterology & Hepatology, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. dengkai@wchscu.cn.
Sichuan University · CNSecond People’s Hospital of Yibin · CNSichuan Cancer Hospital · CNSouthwest Jiaotong University · CNTibet Autonomous Region People's Hospital · CNWest China Hospital of Sichuan University · CNZigong First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether body mass index (BMI) is a risk factor for poor bowel preparation is controversial, and the optimal bowel preparation regimen for people with a high BMI is unclear.

methodsWe prospectively included 710 individuals with high BMIs (≥ 24 kg/m

resultsAfter enrollment, 15 individuals didn't undergo colonoscopy, finally 345 participants took 3 L split-dose PEG regimen, and 350 participants took 2 L PEG regimen for colonoscopic bowel preparation. 3 L split-dose PEG regimen was superior to 2 L PEG regimen in the rate of adequate bowel preparation (81.2% vs. 74.9%, P = 0.045), BBPS score (6.71±1.15 vs. 6.37±1.31, P < 0.001), and the rate of polyp detection (62.0% vs. 52.9%, P = 0.015). The cecal intubation rate was similar in both groups (99.7%). Regarding adverse reactions, individuals were more likely to feel nausea in the 3 L PEG group (30.9% vs. 19.3%; P = 0.001); however, the degree was mild. In the subgroup analysis for adequate bowel preparation, 3 L split-dose PEG regimen performed better than 2 L PEG regimen in the overweight (BMI 25-29.9 kg/m

conclusions3 L split-dose PEG regimen is superior to 2 L PEG regimen for colonoscopic Bowel Preparation in relatively high-BMI individuals, especially overweight individuals (BMI 25-29.9 kg/m

trial registrationThis trial was registered in the Chinese Clinical Trials Registry (ChiCTR2000039068). The date of first registration, 15/10/2020, http://www.chictr.org.cn.

Indexed as

CatharticsPolyethylene GlycolsBody Mass IndexCecumColonoscopyHumansOverweightPolypsCatharticsPolyethylene GlycolsBody mass indexBowel preparationColonoscopyPolyethylene glycolPolyp detection

Identifiers

PMID38053082
PMCPMC10698874
OpenAlexW4389329656

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.