Evidence map›Paper›PMID 38053078›Full record

ArticleBMC bioinformatics2023

G-bic: generating synthetic benchmarks for biclustering.

Eduardo N Castanho, João P Lobo, Rui Henriques, Sara C Madeira

Erratum issuedAbstract read
In one paragraph

Article in BMC bioinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biclustering data analysis: a comprehensive survey.Briefings in bioinformatics · 2024
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Eduardo N Castanho *LASIGE, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 016, 1749-016, Lisbon, Portugal. ejcastanho@ciencias.ulisboa.pt.
João P Lobo *LASIGE, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 016, 1749-016, Lisbon, Portugal.
Rui HenriquesINESC-ID, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1900-001, Lisbon, Portugal.
Sara C MadeiraLASIGE, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 016, 1749-016, Lisbon, Portugal.

Funding

Fundação para a Ciência e a Tecnologia 2021.07810.BDFundação para a Ciência e a Tecnologia DSAIPA/AI/0033/2019H2020-RIA 818290INESC-ID Research Unit UIDB/50021/2020LASIGE Research Unit UIDB/00408/2020
6 · The paper itself

Abstract

backgroundBiclustering is increasingly used in biomedical data analysis, recommendation tasks, and text mining domains, with hundreds of biclustering algorithms proposed. When assessing the performance of these algorithms, more than real datasets are required as they do not offer a solid ground truth. Synthetic data surpass this limitation by producing reference solutions to be compared with the found patterns. However, generating synthetic datasets is challenging since the generated data must ensure reproducibility, pattern representativity, and real data resemblance.

resultsWe propose G-Bic, a dataset generator conceived to produce synthetic benchmarks for the normative assessment of biclustering algorithms. Beyond expanding on aspects of pattern coherence, data quality, and positioning properties, it further handles specificities related to mixed-type datasets and time-series data.G-Bic has the flexibility to replicate real data regularities from diverse domains. We provide the default configurations to generate reproducible benchmarks to evaluate and compare diverse aspects of biclustering algorithms. Additionally, we discuss empirical strategies to simulate the properties of real data.

conclusionG-Bic is a parametrizable generator for biclustering analysis, offering a solid means to assess biclustering solutions according to internal and external metrics robustly.

Indexed as

Gene Expression ProfilingAlgorithmsCluster AnalysisReproducibility of ResultsBiclusteringSynthetic data generatorTime series analysisUnsupervised learning

Identifiers

PMID38053078
PMCPMC10698934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.