Evidence map›Paper›PMID 38052994›Full record

ArticleAnalytical and bioanalytical chemistry2024

Simultaneous detection of AFB1 and aflD gene by "Y" shaped aptamer fluorescent biosensor based on double quantum dots.

Yaqi Li, Qingyue Sun, Xin Chen, Shuangfeng Peng, Dezhao Kong, Chang Liu, Qi Zhang, Qiaoqiao Shi, Yong Chen

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yaqi LiSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China. liyaqi@just.edu.cn.
Qingyue SunSchool of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Xin ChenSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Shuangfeng PengSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Dezhao KongSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Chang LiuSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Qi ZhangSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Qiaoqiao ShiSchool of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang, 212100, Jiangsu Province, People's Republic of China.
Yong ChenSchool of Environmental Science and Engineering, Huazhong University of Science and Technology, Wuhan, 430074, Hubei Province, People's Republic of China. ychen@mail.hust.edu.cn.
Jiangsu University of Science and Technology · CNHuazhong University of Science and Technology · CN

Funding

the China Postdoctoral Science Foundation 2021M692370the National Natural Science Foundation of China 31901799
6 · The paper itself

Abstract

The developed method for simultaneous detection of aflatoxin B1 (AFB1) and aflD genes can effectively monitor from the source and reduce the safety problems and economic losses caused by the production of aflatoxin, which can be of great significance for food safety regulations. In this paper, we constructed a sensitive and convenient fluorescent biosensor to detect AFB1 and aflD genes simultaneously based on fluorescence resonance energy transfer (FRET) between quantum dots (QDs) and a black hole quenching agent. A stable "Y" shaped aptasensor was employed as the detection platform and a double quantum dot labeled DNA fragment was utilized to be the sensing element in this work. When the targets of AFB1 and aflD genes were presented in the solution, the aptamer in the "Y" shaped probe is specifically recognized by the target. At this time, both Si-carbon quantum dots (Si-CDs) and CdTe QDs are far away from the BHQ1 and BHQ3 to recover the fluorescence. The linear range of the prepared fluorescence simultaneous detection method was as wide as 0.5-500 ng·mL

Indexed as

Aptamers, NucleotideBiosensing TechniquesCadmium CompoundsQuantum DotsAflatoxin B1Fluorescent DyesLimit of DetectionTelluriumAflatoxin B1Aptamers, NucleotideCadmium Compoundscadmium tellurideFluorescent DyesTelluriumAFB1AflD geneFluorescence resonance energy transferSimultaneous detection“Y” shaped aptamer

Identifiers

PMID38052994
OpenAlexW4389358957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.