Evidence map›Paper›PMID 38052920›Full record

ArticleScientific reports2023

Correlation between dynamic contrast-enhanced MRI characteristics and apparent diffusion coefficient with Ki-67-positive expression in non-mass enhancement of breast cancer.

Tingting Nie, Mengwei Feng, Kai Yang, Xiaofang Guo, Zilong Yuan, Zhaoxi Zhang, Gen Yan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tingting Nie *Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China.
Mengwei Feng *Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China.
Kai YangDepartment of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China.
Xiaofang GuoDepartment of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China.
Zilong YuanDepartment of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China.
Zhaoxi ZhangDepartment of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, No 116 Zhuodaoquan South Load, Hongshan District, Wuhan, 430079, Hubei, China. zzx6367620@sina.com.
Gen YanDepartment of Radiology, the Second Affiliated Hospital of Xiamen Medical College, No 566 Shengguang Road, Jimei District, Xiamen, 361000, Fujian, China. gyan@stu.edu.cn.
Hubei Cancer Hospital · CNJimei University · CN

Funding

Cancer Research Program of National Cancer Center (NCC201917B05)Special Project of Biomedical Research Center of Hubei Cancer Hospital (2022SWZX06)the Institute of Respiratory of Diseases, Xiamen medical college (grant number HXJB-15)
6 · The paper itself

Abstract

As a remarkably specific characteristic of breast cancer observed on magnetic resonance imaging (MRI), the association between the NME type breast cancer and prognosis, including Ki-67, necessitates comprehensive exploration. To investigate the correlation between dynamic contrast-enhanced MRI (DCE-MRI) characteristics and apparent diffusion coefficient (ADC) values with Ki-67-positive expression in NME type breast cancer. A total of 63 NME type breast cancer patients were retrospectively reviewed. Malignancies were confirmed by surgical pathology. All patients underwent DCE and diffusion-weighted imaging (DWI) before surgery. DCE-MRI characteristics, including tumor distribution, internal enhancement pattern, axillary adenopathy, and time-intensity curve types were observed. ADC values and lesion sizes were also measured. The correlation between these features and Ki-67 expression were assessed using Chi-square test, Fisher's exact test, and Spearman rank analysis. The receiver operating characteristic curve and area under the curve (AUC) was used to evaluate the diagnostic performance of Ki-67-positive expression. Regional distribution, TIC type, and ipsilateral axillary lymph node enlargement were correlated with Ki-67-positive expression (χ

Indexed as

Breast NeoplasmsContrast MediaDiffusion Magnetic Resonance ImagingFemaleHumansKi-67 AntigenMagnetic Resonance ImagingRetrospective StudiesContrast MediaKi-67 Antigen

Identifiers

PMID38052920
PMCPMC10698184
OpenAlexW4389336445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.