Evidence map›Paper›PMID 38052890›Full record

ArticleAbdominal radiology (New York)2024

Intravoxel incoherent motion diffusion-weighted imaging for evaluating the pancreatic perfusion in cirrhotic patients.

Ran Hu, Guo-Fei Zeng, Yu Fang, Lisha Nie, Hui-Lou Liang, Zhi-Gang Wang, Hua Yang

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Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ran HuDepartment of Radiology, Chongqing Hospital of Traditional Chinese Medicine, No.6, Panxi 7th Road, Jiangbei District, Chongqing, 400021, People's Republic of China.ORCID http://orcid.org/0000-0002-6010-5299
Guo-Fei ZengDepartment of Radiology, Chongqing Hospital of Traditional Chinese Medicine, No.6, Panxi 7th Road, Jiangbei District, Chongqing, 400021, People's Republic of China.
Yu FangDepartment of Radiology, Chongqing Hospital of Traditional Chinese Medicine, No.6, Panxi 7th Road, Jiangbei District, Chongqing, 400021, People's Republic of China.
Lisha NieGE Healthcare, MR Research China, Beijing, People's Republic of China.
Hui-Lou LiangGE Healthcare, MR Research China, Beijing, People's Republic of China.
Zhi-Gang WangDepartment of Ultrasound, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong Distinct, Chongqing, 400010, People's Republic of China. wangzhigang@cqmu.edu.cn.
Hua YangDepartment of Radiology, Chongqing Hospital of Traditional Chinese Medicine, No.6, Panxi 7th Road, Jiangbei District, Chongqing, 400021, People's Republic of China. 13527547568@163.com.
First People's Hospital of Chongqing · CNDalian Medical University · CN

Funding

Key Project of Application Development Plan of Chongqing cstc2019jscx-dxwt BX0004the National Natural Science Foundation of China 82172092
6 · The paper itself

Abstract

purposeTo assess the characteristics of pancreatic perfusion in normal pancreas versus cirrhotic patients using intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI).

methodsA total of 67 cirrhotic patients and 33 healthy subjects underwent IVIM on a 3.0 T MRI scanner. Diffusion coefficient (ADC

resultsThe f value of the pancreas in cirrhotic patients was significantly lower than that in normal subjects (p = 0.01). In the cirrhotic group, the f value of the pancreas decreased with the increase of the Child-Pugh classification (R = - 0.49, p = 0.00). The f value of the pancreas was significantly higher in Child-Pugh class A patients than in class B and C patients (p = 0.02, 0.00, respectively), whereas there was no significant difference between class B and C patients (p = 0.16).

conclusionThe IVIM-derived perfusion-related parameter (f value) could be helpful for the evaluation of pancreatic perfusion in liver cirrhosis. Our data also suggest that the blood perfusion decrease in the pancreas is present in liver cirrhosis, and the pancreatic perfusion tends to decrease with the increasing severity of hepatic function.

trial registrationTrial registration number is 2021-ky-68 and date of registration for prospectively registered trials is February 23, 2022.

Indexed as

Diffusion Magnetic Resonance ImagingPancreasHumansLiver CirrhosisMagnetic Resonance ImagingPerfusionIVIMLiver cirrhosisMRIPancreasPerfusion

Identifiers

PMID38052890
OpenAlexW4389334459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.