Evidence map›Paper›PMID 38052776›Full record

ArticleNature communications2023

National genomic surveillance integrating standardized quantitative susceptibility testing clarifies antimicrobial resistance in Enterobacterales.

Shizuo Kayama, Koji Yahara, Yo Sugawara, Sayoko Kawakami, Kohei Kondo, Hui Zuo, Shoko Kutsuno, Norikazu Kitamura, Aki Hirabayashi, Toshiki Kajihara and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Phenotypic and Genetic Characteristics ofInternational journal of molecular sciences · 2026
    Article
  4. Investigation of carbapenem-hydrolysingJournal of medical microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Phenotypic and genome-based characterization ofFrontiers in microbiology · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Genomic characterization of extended-spectrum β-lactamase-producingApplied and environmental microbiology · 2025
    Article
  13. Review
  14. Cancer cell-extrinsic STING shapes immune-active microenvironment and predicts clinical outcome in gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  15. Article
  16. Article
  17. Molecular analysis of AmpC-producing Escherichia coli isolated from pediatric patients.Journal of the Pediatric Infectious Diseases Society · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Shizuo Kayama *Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan. kayama@niid.go.jp.ORCID 0000-0003-2420-3542
Koji Yahara *Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan. k-yahara@niid.go.jp.ORCID 0000-0003-4289-1115
Yo SugawaraAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan. suga-yo@niid.go.jp.ORCID 0000-0002-9897-3905
Sayoko KawakamiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Kohei KondoAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Hui ZuoAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Shoko KutsunoAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Norikazu KitamuraAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Aki HirabayashiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Toshiki KajiharaAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Hitomi KurosuAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Liansheng YuAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Masato SuzukiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Junzo HisatsuneAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Motoyuki SugaiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan. sugai@niid.go.jp.
National Institute of Infectious Diseases · JP

Funding

Japan Agency for Medical Research and Development (AMED) 21fk0108604
6 · The paper itself

Abstract

Antimicrobial resistance is a global health concern; Enterobacterales resistant to third-generation cephalosporins (3GCs) and carbapenems are of the highest priority. Here, we conducted genome sequencing and standardized quantitative antimicrobial susceptibility testing of 4,195 isolates of Escherichia coli and Klebsiella pneumoniae resistant to 3GCs and Enterobacterales with reduced meropenem susceptibility collected across Japan. Our analyses provided a complete classification of 3GC resistance mechanisms. Analyses with complete reference plasmids revealed that among the bla

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialBacterial Proteinsbeta-LactamasesCarbapenemsEscherichia coliGenomicsMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenems

Identifiers

PMID38052776
PMCPMC10698200
OpenAlexW4389362949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.