Evidence map›Paper›PMID 38052209›Full record

ArticleCell reports methods2023

Brain-wide circuit-specific targeting of astrocytes.

Alyssa Thompson, Rachel Arano, Uzair Saleem, Rebecca Preciado, Lizbeth Munoz, Ian Nelson, Katarina Ramos, Yerim Kim, Ying Li, Wei Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports methods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alyssa ThompsonDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Rachel AranoDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Uzair SaleemDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Rebecca PreciadoDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Lizbeth MunozDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ian NelsonDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Katarina RamosDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Yerim KimDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ying LiDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ying1.li@utsouthwestern.edu.
Wei XuDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: wei.xu1@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USSouthwestern Medical Center · US

Funding

Cell Type-specific Anterograde Circuit Mapping and Functional Control by Optimizing YFV-17D Transneuronal SystemsRF1MH130422 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI XU, WEI · 2022 to 2022
$1.6M
NIMH NIH HHS RF1 MH130422
6 · The paper itself

Abstract

Astrocytes are integral components of brain circuitry. They enwrap synapses, react to neuronal activity, and regulate synaptic transmission. Astrocytes are heterogeneous and exhibit distinct features and functions in different circuits. Selectively targeting the astrocytes associated with a given neuronal circuit would enable elucidation of their circuit-specific functions but has been technically challenging to date. Recently, we constructed anterograde transneuronal viral vectors based on yellow fever vaccine YFV-17D. Among them, the replication-incompetent YFV

Indexed as

AstrocytesYellow Fever VaccineBrainNeuronsSynapsesYellow Fever VaccineanterogradeastrocytescircuitCP: Neuroscienceglialselective targetingsynapsetransneuronal targetingYFV-17D

Identifiers

PMID38052209
PMCPMC10753298
OpenAlexW4389306288

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.