Evidence map›Paper›PMID 38052116›Full record

ReviewCurrent opinion in genetics & development2024

Topical section: embryonic models (2023) for Current Opinion in Genetics & Development.

Charlotte E Handford, Sergi Junyent, Victoria Jorgensen, Magdalena Zernicka-Goetz

Abstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Compensation of gene dosage on the mammalian X.Development (Cambridge, England) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Charlotte E HandfordDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. Electronic address: https://twitter.com/@CEHandford.
Sergi JunyentDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. Electronic address: https://twitter.com/@JunyentSergi.
Victoria JorgensenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Magdalena Zernicka-GoetzDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. Electronic address: magdaz@caltech.edu.

Funding

Placental models to support embryogenesis in vitroDP1HD104575 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ZERNICKA-GOETZ, MAGDALENA · 2020 to 2024
$5.8M
European Research CouncilNICHD NIH HHS DP1 HD104575Wellcome Trust
6 · The paper itself

Abstract

Stem cell-based mammalian embryo models facilitate the discovery of developmental mechanisms because they are more amenable to genetic and epigenetic perturbations than natural embryos. Here, we highlight exciting recent advances that have yielded a plethora of models of embryonic development. Imperfections in these models highlight gaps in our current understanding and outline future research directions, ushering in an exciting new era for embryology.

Indexed as

Embryo, MammalianEmbryonic DevelopmentAnimalsFemaleMammalsOrganogenesisPregnancyStem Cells

Identifiers

PMID38052116
PMCPMC11556421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.