Evidence map›Paper›PMID 38052095›Full record

ArticleFamily practice2024

The long-term impacts of opioid use before and after joint arthroplasty: matched cohort analysis of New Zealand linked register data.

Yana Pryymachenko, Ross Wilson, John Haxby Abbott, Michelle Dowsey, Peter Choong

Open access · hybridAbstract read
In one paragraph

Article in Family practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yana PryymachenkoDepartment of Surgical Sciences, Centre for Musculoskeletal Outcomes Research, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-0259-1217
Ross WilsonDepartment of Surgical Sciences, Centre for Musculoskeletal Outcomes Research, University of Otago, Dunedin, New Zealand.ORCID 0000-0001-8505-8081
John Haxby AbbottDepartment of Surgical Sciences, Centre for Musculoskeletal Outcomes Research, University of Otago, Dunedin, New Zealand.ORCID 0000-0001-6468-7284
Michelle DowseyDepartment of Surgery, St Vincent's Hospital, University of Melbourne, Melbourne, Australia.ORCID 0000-0002-9708-5308
Peter ChoongDepartment of Surgery, St Vincent's Hospital, University of Melbourne, Melbourne, Australia.ORCID 0000-0002-3522-7374
University of Otago · NZThe University of Melbourne · AU

Funding

Lottery Health Research 2021-152330
6 · The paper itself

Abstract

backgroundOpioids are commonly used both before and after total joint arthroplasty (TJA).

objectiveThe objective of this study was to estimate the long-term effects of pre- and perioperative opioid use in patients undergoing TJA.

methodsWe used linked population datasets to identify all (n =18,666) patients who had a publicly funded TJA in New Zealand between 2011 and 2013. We used propensity score matching to match individuals who used opioids either before surgery, during hospital stay, or immediately post-discharge with individuals who did not based on a comprehensive set of covariates. Regression analysis was used to estimate the effect of opioid use on health and socio-economic outcomes over 5 years.

resultsOpioid use in the 3 months prior to surgery was associated with significant increases in healthcare utilization and costs (number of hospitalizations 6%, days spent in hospital 14.4%, opioid scripts dispensed 181%, and total healthcare costs 11%). Also increased were the rate of receiving social benefits (2 percentage points) and the rates of opioid overdose (0.5 percentage points) and mortality (3 percentage points). Opioid use during hospital stay or post-discharge was associated with increased long-term opioid use, but there was little evidence of other adverse effects.

conclusionsOpioid use before TJA is associated with significant negative health and economic consequences and should be limited. This has implications for opioid prescribing in primary care. There is little evidence that peri- or post-operative opioid use is associated with significant long-term detriments.

Indexed as

Analgesics, OpioidPostoperative PainRegistriesAdultAgedArthroplasty, ReplacementCohort StudiesFemaleHealth Care CostsHospitalizationHumansLength of StayMaleMiddle AgedNew ZealandPatient Acceptance of Health CareAnalgesics, Opioidcohort analysisjoint replacementNew Zealandopioidsosteoarthritispropensity score

Identifiers

PMID38052095
PMCPMC11636625
OpenAlexW4389328516

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.