Evidence map›Paper›PMID 38051914›Full record

ArticleAccounts of chemical research2023

Copper-Catalyzed Benzylic C-H Cross-Coupling Enabled by Redox Buffers: Expanding Synthetic Access to Three-Dimensional Chemical Space.

Si-Jie Chen, Shane W Krska, Shannon S Stahl

Abstract read
In one paragraph

Article in Accounts of chemical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. C(spAngewandte Chemie (International ed. in English) · 2024
    Article
  5. Benzylic C(spBeilstein journal of organic chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Si-Jie ChenDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States.ORCID 0000-0001-9836-6892
Shane W KrskaDepartment of Discovery Chemistry, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States.ORCID 0000-0001-9757-9036
Shannon S StahlDepartment of Chemistry, University of Wisconsin─Madison, 1101 University Avenue, Madison, Wisconsin 53706, United States.ORCID 0000-0002-9000-7665

Funding

Catalytic Redox Reactions for Pharmaceutical SynthesisR35GM134929 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Shannon S Stahl · 2020 to 2026
$4.3M
Radical Relay Methods for Selective C-H OxidationR01GM126832 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI STAHL, SHANNON S · 2018 to 2019
$595k
QExactive (Orbitrap) mass spectrometerS10OD020022 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VESTLING, MARTHA M · 2015 to 2015
$483k
The Development of Enantioselective Nickel Catalysts for Late Stage Functionalization of Benzylic C–H BondsF32GM129909 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BUSS, JOSHUA A · 2018 to 2019
$109k
NIGMS NIH HHS F32 GM129909NIGMS NIH HHS R01 GM126832NIGMS NIH HHS R35 GM134929NIH HHS S10 OD020022
6 · The paper itself

Abstract

ConspectusCross-coupling methods are the most widely used synthetic methods in medicinal chemistry. Existing reactions are dominated by methods such as amide coupling and arylation reactions that form bonds to sp

Identifiers

PMID38051914
PMCPMC10902864

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.