ArticleJournal of nephrology2024
Risk factors and outcomes associated with pregnancy-related acute kidney injury in a high-risk cohort of women in Nigeria.
Article in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- Incidence of acute kidney injury and associated mortality in Nigeria: systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Incidence of pregnancy-associated acute kidney injury in low- and middle-income countries: a meta-analysis.Bulletin of the World Health Organization · 2025Pooled it
- Prevalence and trends of pregnancy-related acute kidney injury in sub-Saharan Africa: a systematic review and meta-analysis.Journal of nephrology · 2025Pooled it
- The association between intraoperative hypotension and postoperative acute kidney injury following emergent critical cesarean delivery: a retrospective cohort study.Journal of clinical monitoring and computing · 2026Article
- Global incidence of acute kidney injury and renal replacement therapy among obstetric intensive care unit admissions: a systematic review and meta-analysis.Journal of anesthesia, analgesia and critical care · 2026Article
- Pregnancy-associated acute kidney injury - consensus report of the 32nd Acute Disease Quality Initiative workgroup.Nature reviews. Nephrology · 2025Article
- Pregnancy-Related Acute Kidney Injury: Causes and Its Impact on Perinatal Outcomes-A Systematic Review.Journal of clinical medicine · 2025Review
- Pregnancy-related acute kidney injury (PrAKI): a call for a uniform reporting approach : Editorial comment on Risk factors and outcomes associated with pregnancy-related acute kidney injury in a high-risk cohort of women in Nigeria.Journal of nephrology · 2024Article
- Women should not die of pregnancy-related acute kidney injury (PRAKI): revealing the underwater iceberg of maternal health.Journal of nephrology · 2024Article
- Spring is here, bringing hope and reflection. A JN issue focused on mothers and children, education, doubts and inequality.Journal of nephrology · 2024Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
introductionDespite a decline in developed countries, pregnancy-related acute kidney injury (PRAKI) remains a significant contributor to maternal mortality and adverse fetal outcomes in resource-constrained settings. Little is known about the impact of pregnancy-related acute kidney injury in Nigeria. Therefore, this study aimed to assess the incidence and maternal-fetal outcomes associated with pregnancy-related acute kidney injury among a cohort of high-risk women in Nigeria.
methodsThis prospective multicenter study included women at high risk of acute kidney injury, who were more than 20 weeks pregnant or within 6 weeks postpartum and admitted to the Obstetrics and Gynecology units of two large public hospitals between September 1, 2019, and July 31, 2022. Acute kidney injury was defined and classified using the Kidney Disease Improving Global Outcomes (KDIGO) criteria.
resultsA total of 433 women, with mean age (± standard deviation) of 28 ± 6 years, were included in the evaluation. Pregnancy-related acute kidney injury occurred in 113 women (26.1%; 95% confidence interval [CI]: 21.1%-30.2%). The leading cause was preeclampsia (n = 57; 50.1%); 19 women died (4.4%), with 17 deaths (15%) occurring in the PRAKI group. Increasing severity of pregnancy-related acute kidney injury was independently associated with maternal mortality: adjusted odds ratio (aOR) for KDIGO stage 2 = 4.40; 95% CI 0.66-29.34, p = 0.13, and KDIGO stage 3 aOR = 6.12; 95% CI 1.09-34.34, p = 0.04. The overall perinatal mortality was 15% (n = 65), with 28 deaths (24.8%) occurring in the PRAKI group. Pregnancy-related acute kidney injury was also associated with an increased risk of perinatal mortality, aOR = 2.23; 95 CI 1.17-4.23, p = 0.02.
conclusionsThe incidence of pregnancy-related acute kidney injury was high, and significantly associated with maternal and perinatal mortality. The leading causes were hypertensive disorders of pregnancy.
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