ArticleThe European physical journal. E, Soft matter2023
Spontaneous bilayer wrapping of virus particles by a phospholipid Langmuir monolayer.
Article in The European physical journal. E, Soft matter, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors at 2 institutions in 2 countries.
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Abstract
We report here the spontaneous formation of lipid-bilayer-wrapped virus particles, following the injection of "naked" virus particles into the subphase of a Langmuir trough with a liquid monolayer of lipids at its air-water interface. The virus particles are those of the well-studied cowpea chlorotic mottle virus, CCMV, which are negatively charged at the pH 6 of the subphase; the lipids are a 9:1 mix of neutral DMPC and cationic CTAB molecules. Before adding CCMV particles to the subphase we establish the mixed lipid monolayer in its liquid-expanded state at a fixed pressure (17.5 mN/m) and average area-per-molecule of (41Å
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