Evidence map›Paper›PMID 38051383›Full record

ReviewCurrent HIV/AIDS reports2023

Awareness of Heightened Sexual and Behavioral Vulnerability as a Trigger for PrEP Resumption Among Adolescent Girls and Young Women in East and Southern Africa.

Krishnaveni Reddy, Thesla Palanee-Phillips, Renee Heffron

Open access · hybridAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Krishnaveni ReddyWits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. kreddy@wrhi.ac.za.
Thesla Palanee-PhillipsWits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Renee HeffronUniversity of Alabama at Birmingham, Birmingham, AL, USA.
University of the Witwatersrand · ZAUniversity of Alabama at Birmingham · US

Funding

Feasibility pilot of home-based STI testing and risk self-assessment among adolescent girls in South Africa to trigger PrEP re-startR34MH126743 · NIMH · WITS HEALTH CONSORTIUM (PTY), LTD · PI HEFFRON, RENEE A., PALANEE, THESLA · 2021 to 2023
$586k
NIMH NIH HHS R34 MH126743
6 · The paper itself

Abstract

purpose of reviewEast and Southern Africa are the epicenter of the HIV epidemic. High HIV incidence rates among adolescent girls and young women (AGYW) remain stable over the last decade despite access to daily oral PrEP. Some settings have experienced high PrEP uptake among AGYW; however, discontinuation has been high. This review sought to understand drivers of PrEP discontinuation in this population in order to identify potential mechanisms to facilitate PrEP restart and optimize PrEP use. RECENT

findingsDrivers of PrEP discontinuation included low perceived HIV acquisition risk, PrEP-associated side effects, pill burden, family/sexual partner disapproval, lack of/intermittent sexual activity, PrEP use stigma, fear of intimate partner violence, misinformation about long-term PrEP use, and limited/inconsistent access to PrEP. The most frequently reported driver of PrEP discontinuation was low perceived HIV acquisition risk. This indicates that innovative interventions to help AGYW recognize their HIV risk and make informed decisions about PrEP use are urgently needed.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentAfrica, SouthernFemaleHumansSexual BehaviorSouth AfricaAnti-HIV AgentsAdolescentsHIV vulnerabilityOral PrEPRestart

Identifiers

PMID38051383
PMCPMC10719120
OpenAlexW4389333276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.