Evidence map›Paper›PMID 38051190›Full record

ArticleRadiology2023

Comparison of Photon-counting Detector and Energy-integrating Detector CT for Visual Estimation of Coronary Percent Luminal Stenosis.

Cynthia H McCollough, Prabhakar Rajiah, John P Bois, Tim N Winfree, Rickey E Carter, Kishore Rajendran, Eric E Williamson, Jamison E Thorne, Shuai Leng

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Cardiac imaging using photon counting CT - benefits, challenges and prospects.The international journal of cardiovascular imaging · 2026
    Review
  7. Article
  8. Review
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  13. Review
  14. Article
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  16. Article
  17. Photon-counting detector computed tomography in cardiac imaging.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cynthia H McColloughFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-5346-332X
Prabhakar RajiahFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0001-7538-385X
John P BoisFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).
Tim N WinfreeFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-8181-5249
Rickey E CarterFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-0818-273X
Kishore RajendranFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-8314-3642
Eric E WilliamsonFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-2066-9612
Jamison E ThorneFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0003-3993-6423
Shuai LengFrom the Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (C.H.M., P.R., J.P.B., T.N.W., K.R., E.E.W., J.E.T., S.L.); and Department of Health Science Research, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-6453-9481
Mayo Clinic · US

Funding

Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
NIBIB NIH HHS R01 EB028590
6 · The paper itself

Abstract

Background Compared with energy-integrating detector (EID) CT, the improved resolution of photon-counting detector (PCD) CT coupled with high-energy virtual monoenergetic images (VMIs) has been shown to decrease calcium blooming on images in phantoms and cadaveric specimens. Purpose To determine the impact of dual-source PCD CT on visual and quantitative estimation of percent diameter luminal stenosis compared with dual-source EID CT in patients. Materials and Methods This prospective study recruited consecutive adult patients from an outpatient facility between January and March 2022. Study participants underwent clinical dual-source EID coronary CT angiography followed by a research dual-source PCD CT examination. For PCD CT, multienergy data were used to create VMIs at 50 and 100 keV. Two readers independently reviewed EID CT images followed by PCD CT images after a washout period. Readers visually graded the most severe stenosis in terms of percent diameter luminal stenosis for the left main, left anterior descending, right, and circumflex coronary arteries, unblinded to scanner type. Quantitative measures of percent stenosis were made using commercial software. Visual and quantitative estimates of percent stenosis were compared between EID CT and PCD CT using the Wilcoxon signed-rank test. Results A total of 25 participants (median age, 59 years [range, 18-78 years]; 16 male participants) were enrolled. On EID CT images, readers 1 and 2 identified 39 and 32 luminal stenoses, respectively, with a percent diameter luminal stenosis greater than 0%. Visual estimates of percent stenosis were lower on PCD CT images than EID CT images (reader 1: median 20.6% [IQR, 8.8%-61.2%] vs 31.8% [IQR, 12.9%-69.7%],

Indexed as

Computed Tomography AngiographyTomography, X-Ray ComputedAdolescentAdultAgedConstriction, PathologicCoronary AngiographyFemaleHumansMaleMiddle AgedPhantoms, ImagingPhotonsProspective StudiesYoung Adult

Identifiers

PMID38051190
PMCPMC10741385
OpenAlexW4389335622

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.