Evidence map›Paper›PMID 38050607›Full record

ArticlePeerJ2023

Amlodipine and lufenuron as repurposing drugs against

Vanice Rodrigues Poester, Jéssica Estefania Dávila Hidalgo, Lara Severo Jardim, Mariana Rodrigues Trápaga, Vanessa Brito de Souza Rabello, Rodrigo Almeida-Paes, Rosely Maria Zancope-Oliveira, Melissa Orzechowski Xavier

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vanice Rodrigues PoesterPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Jéssica Estefania Dávila HidalgoLaboratório de Micologia (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Lara Severo JardimLaboratório de Micologia (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Mariana Rodrigues TrápagaPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Vanessa Brito de Souza RabelloLaboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro state, Brazil.
Rodrigo Almeida-PaesLaboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro state, Brazil.
Rosely Maria Zancope-OliveiraLaboratório de Micologia, Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro state, Brazil.
Melissa Orzechowski XavierPrograma de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina (FAMED), Universidade Federal do Rio Grande (FURG), Rio Grande, Rio Grande do Sul, Brazil.
Universidade Federal do Rio Grande · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sporotrichosis caused by Methods: Twenty clinical isolates of Results: AML showed inhibitory and fungicidal activity against all isolates included, with MIC values ranging from 32 to 256 µg/mL, and MFC from 64 to 256 µg/mL. However, none of the Conclusion: Both repurposing drugs evaluated in our study showed a promising

Indexed as

Antifungal AgentsLeukemia, Myeloid, AcuteAmlodipineBenzamidesDrug RepositioningFluorocarbonsHumansItraconazoleOrganic ChemicalsSporothrixAmlodipineAntifungal AgentsBenzamidesFluorocarbonsfluphenacurItraconazoleLUFOrganic ChemicalsAntifungalPre-clinical testsSporothrix spp.Zoonosis

Identifiers

PMID38050607
PMCPMC10693817
OpenAlexW4389200174

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.