ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024
Forced Abstinence from Volitional Ethanol Intake Drives a Vulnerable Period of Hyperexcitability in BNST-Projecting Insular Cortex Neurons.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- From Efference Copy to Emotional State: Insular Cortex Somatostatin Neurons Buffer Adaptive Responses to Physical Stress.Biological psychiatry global open science · 2026Article
- Association of stress-sensitive mid-insula activity with alcohol drinking and negative affect-like behavior during abstinence in mice.Neuropharmacology · 2026Article
- Adolescent onset of volitional ethanol intake normalizes sex differences observed with adult-onset ethanol intake and negative affective behaviors during protracted forced abstinence.Psychopharmacology · 2026Article
- Anterior insular cortex regulates depression-like and ASD-like behaviors via the differential contribution of two subsets of microglia.Molecular psychiatry · 2026Article
- AlteredbioRxiv : the preprint server for biology · 2025Article
- The Insular Cortex→Bed Nucleus of the Stria Terminalis Pathway during Early Abstinence from Chronic Alcohol Use: A Promising Target for Mitigating Negative Emotions and Relapse Risk.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The insular cortex (IC) integrates sensory and interoceptive cues to inform downstream circuitry executing adaptive behavioral responses. The IC communicates with areas involved canonically in stress and motivation. IC projections govern stress and ethanol recruitment of bed nucleus of the stria terminalis (BNST) activity necessary for the emergence of negative affective behaviors during alcohol abstinence. Here, we assess the impact of the chronic drinking forced abstinence (CDFA) volitional home cage ethanol intake paradigm on synaptic and excitable properties of IC neurons that project to the BNST (IC
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Registered trials
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