Evidence map›Paper›PMID 38049916›Full record

ArticleMilitary Medical Research2023

BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition.

Yu Meng, Hui-Yan Sun, Yi He, Qian Zhou, Yi-Huang Liu, Hui Su, Ming-Zhu Yin, Fu-Rong Zeng, Xiang Chen, Guang-Tong Deng

Open access · diamondAbstract readLetter
In one paragraph

Article in Military Medical Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 22 citations in OpenAlex.

  1. The Emerging Role of Ferroptosis in Pediatric Cancer Biology and Therapy.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Inducing ferroptosis to improve cancer therapy: a promising tool for enhancing immunotherapy.Journal of experimental & clinical cancer research : CR · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Cell Death Modalities in Therapy of Melanoma.International journal of molecular sciences · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Ferroptosis and the tumor microenvironment.Journal of experimental & clinical cancer research : CR · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 5 countries.

Yu Meng *Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Hui-Yan Sun *Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Yi He *Department of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Qian ZhouDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Yi-Huang LiuDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Hui SuDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Ming-Zhu YinDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Fu-Rong ZengDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, China. zengflorachn@hotmail.com.
Xiang ChenDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China. chenxiangck@126.com.
Guang-Tong DengDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, 410008, China. dengguangtong@outlook.com.ORCID 0000-0002-4424-9727
Central South University · CN

Funding

National Key Research and Development Program 2022YFC2504700National Natural Science Foundation of China 82102803National Natural Science Foundation of China 82103183National Natural Science Foundation of China 82272849Natural Science Foundation of Hunan Province 2021JJ40976Natural Science Foundation of Hunan Province 2022JJ40767
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsFerroptosisMelanoma3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)HumansHydroxysteroid DehydrogenasesImmunotherapy3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)AKR1C2 protein, humanAntineoplastic AgentsHydroxysteroid DehydrogenasesAKR1C2Bromodomain and extra terminal domain (BET) inhibitorCell deathFerroptosisImmunotherapyMelanoma

Identifiers

PMID38049916
PMCPMC10694977
OpenAlexW4389303074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.