Evidence map›Paper›PMID 38048897›Full record

ArticleJournal of obstetric, gynecologic, and neonatal nursing : JOGNN2024

Relationships Among Number of Stressors, Perceived Stress, and Salivary Cortisol Levels During the Third Trimester of Pregnancy.

Rebecca Salomon, Sandra Weiss

Registry-linked trialAbstract read
In one paragraph

Article in Journal of obstetric, gynecologic, and neonatal nursing : JOGNN, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06970886 (Effects of Rhythm-Based Music on Anxiety, Glucose, and Cortisol in Pregnancies With Gestational Diabetes), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06970886 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Rhythm-Based Music on Anxiety, Glucose, and Cortisol in Pregnancies With Gestational Diabetes

TypeinterventionalSponsorEsin Ceber Turfan, ProfessorRan2025 to 2027Enrolled180ConditionsGestational Diabetes Mellitus in Pregnancy, Anxiety, Blood Sugar, HighArmsRhythm-Based Music Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rebecca Salomon
Sandra Weiss

Funding

INTERVENTIONS FOR PREVENTING &MANAGING CHRONIC ILLNESST32NR007091 · NINR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Cheryl L Giscombe, Cathi Barbra Propper · 1996 to 2026
$11.8M
Antenatal Corticosteroids, Maternal Depression and Preterm Infant Stress ResponseR01HD081188 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISS, SANDRA JEAN · 2015 to 2019
$2.9M
Biobehavioral Research Training Program in Symptom ScienceT32NR016920 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIASKOWSKI, CHRISTINE A., WEISS, SANDRA JEAN · 2017 to 2021
$2.4M
NICHD NIH HHS R01 HD081188NINR NIH HHS T32 NR007091NINR NIH HHS T32 NR016920
6 · The paper itself

Abstract

objectiveTo examine relationships among the number of stressors, perceived stress, and salivary cortisol levels during the third trimester of pregnancy.

designSecondary analysis of cross-sectional data.

settingParticipants' homes.

participantsWomen during the third trimester of pregnancy (N = 73).

methodsParticipants provided saliva samples at four time points over 2 days for cortisol assay and completed questionnaires to assess stressors and perceived stress. We computed multiple linear regression models to examine the relationships among the number of stressors and perceived stress to cortisol awakening response, diurnal slope, and overall cortisol secretion. We also computed a multiple linear regression model to examine the relationship between perceived stress and the number of stressors.

resultsGreater perceived stress was associated with reduced overall cortisol secretion across the day (β = -0.41, p = .01). The number of stressors was associated with perceived stress (β = 0.48, p = .002) but not salivary cortisol measures.

conclusionElevated perceived stress and the related cortisol alterations that we identified could represent salient targets for enhancing hypothalamic-pituitary-adrenal axis function during the third trimester. Perceived stress may shape the relationship between exposure to stressors and cortisol response during pregnancy. Future research is warranted to confirm study results and to understand the implications for parturition and fetal development.

Indexed as

HydrocortisoneHypothalamo-Hypophyseal SystemCross-Sectional StudiesFemaleHumansPituitary-Adrenal SystemPregnancyPregnancy Trimester, ThirdSalivaStress, PsychologicalHydrocortisonecortisolperceived stresspregnancypsychological stressors

Identifiers

PMID38048897
PMCPMC10939920

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.