ArticleThe lancet. Diabetes & endocrinology2024
Mendelian randomisation at 20 years: how can it avoid hubris, while achieving more?
Article in The lancet. Diabetes & endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Structured tools for assessing quality and risk of bias in Mendelian randomization studies: an updated systematic review.International journal of epidemiology · 2026Pooled it
- Application of Mendelian randomized research method in oncology research: bibliometric analysis.Frontiers in oncology · 2024Pooled it
- Mendelian randomisation in ophthalmology: An overview and practical guide for clinicians.European journal of ophthalmology · 2026Review
- Genetic investigation of non-affective psychosis and depression as causal risk factors for dementia.BMJ mental health · 2026Article
- Quantifying new threats to health and biomedical literature integrity from rapidly scaled publications and problematic research.Journal of clinical epidemiology · 2026Article
- The causal effects of hypothyroidism on cardiovascular disease: Bidirectional and multivariable Mendelian randomization study.Journal of diabetes investigation · 2026Article
- Gene-environment equivalence: The fundamental principle of Mendelian randomization.PLoS medicine · 2026Article
- Potential ofFrontiers in immunology · 2026Article
- Leucine, autoimmune diseases, and circulating mediators shape the causal landscape of lymphoid malignancies.Frontiers in immunology · 2026Article
- Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study.Current issues in molecular biology · 2025Article
- Interactive Effect of Plasma Lipidome on Neuropsychiatric Disorders: A Bidirectional Mendelian Randomization Study.Molecular neurobiology · 2025Article
- Transcriptome-wide Mendelian randomization exploring dynamic CD4+ T cell gene expression in colorectal cancer development.Journal of leukocyte biology · 2025Article
- The rapid growth in Mendelian randomization studies.European journal of epidemiology · 2025Article
- Mendelian Randomization and Infection: Pitfalls and Promises.The Journal of infectious diseases · 2025Review
- Maternal fever, epidural analgesia, and genetics: implications for the neonate.British journal of anaesthesia · 2025Article
- The role of estimation in Mendelian randomization: should Mendelian randomization investigations provide estimates?AJE advances : research in epidemiology · 2025Article
- Genetic Determinants of Left Atrial Function Are Associated With Stroke.Journal of the American Heart Association · 2024Article
- Managing the Exponential Growth of Mendelian Randomization Studies.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Addressing the credibility crisis in Mendelian randomization.BMC medicine · 2024Review
- Reclaiming mendelian randomization from the deluge of papers and misleading findings.Lipids in health and disease · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
38048796What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.