Evidence map›Paper›PMID 38048599›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.

Carla Mariner-Llicer, Belén Saavedra Cervera, Edson Mambuque, Neide Gomes, Shilzia Munguambe, Luis Villamayor, Irving Cancino-Muñoz, Manuela Torres-Puente, Dinis Nguenha, Durval Respeito and 4 more

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Molecular Characterization of theAntibiotics (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Carla Mariner-LlicerTuberculosis Genomics Unit, Instituto de Biomedicina de Valencia (IBV), CSIC, Valencia, Spain.ORCID 0000-0002-8230-5785
Belén Saavedra CerveraISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-4057-0214
Edson MambuqueCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.ORCID 0000-0002-9106-1444
Neide GomesCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Shilzia MunguambeCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Luis VillamayorFISABIO Public Health, Valencia, Spain.
Irving Cancino-MuñozFISABIO Public Health, Valencia, Spain.ORCID 0000-0002-5261-1634
Manuela Torres-PuenteTuberculosis Genomics Unit, Instituto de Biomedicina de Valencia (IBV), CSIC, Valencia, Spain.ORCID 0000-0002-8352-180X
Dinis NguenhaCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.ORCID 0000-0001-9921-2609
Durval RespeitoCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.
Gustavo TembeCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.ORCID 0000-0001-7241-0381
Mariana G LópezTuberculosis Genomics Unit, Instituto de Biomedicina de Valencia (IBV), CSIC, Valencia, Spain.ORCID 0000-0002-2216-9232
Iñaki ComasTuberculosis Genomics Unit, Instituto de Biomedicina de Valencia (IBV), CSIC, Valencia, Spain.ORCID 0000-0001-5504-9408
Alberto L García-BasteiroISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-2038-5505

Funding

NIH HHS
6 · The paper itself

Abstract

Multidrug-resistant(MDR) tuberculosis in Southern Africa is of great concern, exacerbated by the spread of a clone harboring a mutation missed by Xpert Ultra. In Southern Mozambique, the presence of such mutation and rising cases of non-MDR isoniazid resistance highlights the need to ensure accurate detection of antimicrobial-resistance in the country.

Indexed as

Mycobacterium tuberculosisTuberculosis, Multidrug-ResistantDrug Resistance, BacterialHumansMozambiqueMutationRifampinSensitivity and SpecificityRifampinMozambiqueMycobacterium tuberculosisresistance conferring mutationswhole-genome sequencing

Identifiers

PMID38048599
PMCPMC11006097

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.