Evidence map›Paper›PMID 38048450›Full record

ArticleLupus2024

Sociodemographic profiles and organ damage accural in the Black Women's Experience Living with Lupus study.

Connor D Martz, Tamika Webb-Detiege, Maria I Danila, David H Chae

Abstract read
In one paragraph

Article in Lupus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Connor D MartzPopulation Research Center, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0003-3155-0729
Tamika Webb-DetiegeDepartment of Rheumatology, Ochsner Health, New Orleans, LA, USA.
Maria I DanilaDivision of Clinical Immunology and Rheumatology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.
David H ChaeDepartment of Social, Behavioral, and Population Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.

Funding

Training Program in Population StudiesT32HD007081 · NICHD · UNIVERSITY OF TEXAS AUSTIN · PI Aprile Dawn Benner, Abigail Mae Weitzman · 1985 to 2026
$6.8M
Scientific & Technical CoreP2CHD042849 · NICHD · UNIVERSITY OF TEXAS AT AUSTIN · PI MARK D. HAYWARD · 2017 to 2026
$5.2M
Psychosocial Factors and Lupus Disease Progression Among African American WomenR01AR065493 · NIAMS · UNIV OF MARYLAND, COLLEGE PARK · PI CHAE, H. DAVID, LIM, SUNG SAM · 2014 to 2022
$4.2M
Biopsyochosocial Mechanisms of Lupus Progression in African American WomenF31AR076234 · NIAMS · AUBURN UNIVERSITY AT AUBURN · PI MARTZ, CONNOR D. · 2019 to 2020
$78k
NIAMS NIH HHS F31 AR076234NIAMS NIH HHS R01 AR065493NICHD NIH HHS P2C HD042849NICHD NIH HHS T32 HD007081
6 · The paper itself

Abstract

objectiveBlack/African American women with systemic lupus erythematosus (SLE) experience greater organ damage and at younger ages than white women. The objective of this study was to advance research on SLE inequities by identifying sociodemographic risk profiles associated with organ damage accrual specifically among Black/African American women.

methodsLatent profile analysis was conducted among 438 Black/African American women with SLE living in Atlanta, GA and enrolled in the Black Women's Experiences Living with Lupus (BeWELL) Study (May 2015 to April 2017). Proportional hazard and Poisson regression models examined prospective associations between sociodemographic profiles and the timing and degree of organ damage accrual over 2 years.

resultsFour profiles emerged: (1) "Younger/Lower SES with Uncontrolled SLE" (44.8%), (2) "Older/Lower SES with Uncontrolled SLE" (23.3%), (3) "Mid-SES with Controlled SLE" (19.6%), and (4) "Higher SES with Controlled SLE" (11.2%). Approximately 42% of participants experienced new organ damage during the follow-up period. Proportional hazard models indicated that "Older/Lower SES with Uncontrolled SLE" participants were at greatest risk of new organ damage (HR = 2.41; 95% CI = 1.39, 4.19), followed by "Younger/Lower SES with Uncontrolled SLE" participants (HR = 1.56; 95% CI = 0.92, 2.67), compared to those in the "Higher SES with Controlled SLE" profile. Poisson regression models revealed that these two groups also exhibited greater organ damage accrual (b = 0.98, SE = 0.24, 95% CI = 0.52, 1.44 and b = 0.72, SE = 0.23, 95% CI = 0.27, 1.17, respectively).

conclusionsBlack/African American women with fewer socioeconomic resources and uncontrolled SLE are at greatest risk for increasing disease severity over time. Social inequities likely contribute to racial inequities in SLE progression.

Indexed as

Lupus Erythematosus, SystemicBlack or African AmericanFemaleHumansPatient AcuityRacial GroupsSeverity of Illness Indexorgan damageracial disparitiessocioeconomicsystemic lupus erythematosus

Identifiers

PMID38048450
PMCPMC10777614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.