Evidence map›Paper›PMID 38048380›Full record

ArticleInternational health2023

Expanding a photographic grading system for trachomatous scarring.

Yassin Nayel, Beatriz E Muñoz, Harran Mkocha, Sheila K West, Meraf A Wolle

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yassin NayelDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore 21287, MD, USA.ORCID 0000-0003-2112-9420
Beatriz E MuñozDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore 21287, MD, USA.
Harran MkochaKongwa Trachoma Project, Kongwa, United Republic of Tanzania.
Sheila K WestDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore 21287, MD, USA.ORCID 0000-0003-0818-8100
Meraf A WolleDana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore 21287, MD, USA.ORCID 0000-0001-5736-5850
Johns Hopkins University · US

Funding

Trachomatous Trichiasis and Predicting the End of Blinding TrachomaK23EY030162 · NEI · JOHNS HOPKINS UNIVERSITY · PI WOLLE, MERAF A · 2020 to 2022
$638k
NEI NIH HHS K23 EY030162NIH HHS K23 EY030162
6 · The paper itself

Abstract

backgroundThe purpose was to assess an expansion of a previously published photographic four-step severity grading scale for trachomatous scarring (TS).

methodsImages of everted eyelids of adult women in Tanzania were graded for the presence and severity of TS. The previous S3 grade was subdivided into two categories: S3A, one-third to <50% of the upper eyelid conjunctiva scarred; and S3B, 50% to <90%. The reliability and ease of use were evaluated. This new categorisation was then applied to images taken of the same women 5 y prior to evaluate whether it could help detect previously undetected progression.

resultsIn total, 142 eyes at baseline and 418 eyes at follow-up after 5 y were graded as S3. Interobserver agreement using the expanded scarring grading scale was a kappa of 0.86. At baseline, 51 (35.9%) eyes were S3A and 91 (64.1%) were S3B. At follow-up after 5 y, 36.6% of the eyes that were previously documented as not having progressed were now detected as having progressed from S3A to S3B. S3B images were more likely to progress to S4 compared with S3A (OR 4.6, 95% CI 2.1 to 9.9).

conclusionsAdding S3A and S3B is reliable and detects more scarring progression. It will be beneficial for future studies analysing TS in photographs.

Indexed as

CicatrixTrachomaAdultFemaleHumansPhotographyReproducibility of ResultsTanzaniaSAFE strategytrachomatrachomatous scarringtrachomatous trichiasis

Identifiers

PMID38048380
PMCPMC10695455
OpenAlexW4389297767

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.