ArticleACS chemical neuroscience2023
Synthesis and Preclinical Evaluation of 22-[
Open access · hybridAbstract read
In one paragraph
Article in ACS chemical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Development of potent, selective cPLAnpj drug discovery · 2026Article
- Membrane Molecular Species Remodeling as a Signature of ω-3 Fatty Acid Action in Cultured Neural Cells.ASN neuro · 2026Article
- Highlights on U.S. FDA-approved halogen-containing drugs in 2024.European journal of medicinal chemistry · 2025Review
- Effects of APOE4 on omega-3 brain metabolism across the lifespan.Trends in endocrinology and metabolism: TEM · 2024Review
- Highlights on Fluorine-containing Drugs Approved by U.S. FDA in 2023.Current topics in medicinal chemistry · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 5 institutions in 2 countries.
Marlon Vincent V DuroDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Juno Van ValkenburghDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Diana E InglesDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Jenny TranDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Zhiheng CaiDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Brandon EbrightAlfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California 90089, United States.ORCID 0000-0002-8939-6069
Shaowei WangDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Bilal E KermanDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.ORCID 0000-0003-1106-3288
Jasmin GalvanDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Sung Hee HwangDepartment of Entomology and Nematology and UC Davis Comprehensive Cancer Center, University of California, Davis, California 95616, United States.ORCID 0000-0002-9891-928X
Naomi S Sta MariaZilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Francesca ZanderigoDepartment of Psychiatry, Columbia University, New York, New York 10032, United States.
Etienne CroteauSherbrooke Center for Molecular Imaging, University of Sherbrooke, Sherbrooke, QC J1H 4C4, Canada.
Stephen C CunnaneResearch Center on Aging, Department of Medicine, University of Sherbrooke, Sherbrooke, QC J1H 4C4, Canada.
Stanley I RapoportNational Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-9304, United States.
Stan G LouieAlfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California 90089, United States.
Russell E JacobsZilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Hussein N YassineDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
Kai ChenDepartment of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.ORCID 0000-0002-8647-1182
University of Southern California · USUniversité de Sherbrooke · CANational Institute on Alcohol Abuse and Alcoholism · USNew York State Psychiatric InstituteUC Davis Comprehensive Cancer Center
Funding
USCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI, ARTHUR W TOGA · 2020 to 2026
$27.8MThe delivery of essential fatty acids to the Brain in Alzheimer's diseaseR01AG054434 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YASSINE, HUSSEIN N · 2017 to 2021
$5.4MBiomarkers of ABCA1 mediated functions in Alzheimers diseaseR01AG055770 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YASSINE, HUSSEIN N · 2017 to 2021
$4.2MEffect of diabetes and AD pathology on brain imaging and cognition in Latino adultsRF1AG078362 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BORZAGE, MATTHEW, BRASKIE, MEREDITH NICOLE · 2022 to 2022
$3.8MApoE, ABCA1 and endosomal dysregulation in ADR01AG067063 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YASSINE, HUSSEIN N · 2020 to 2024
$3.4MBrain cPLA2 as a mechanism for neuroinflammation in AD/ADRD with and without APOE4 Diversity SupplementRF1AG076124 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARVANITAKIS, ZOE, YASSINE, HUSSEIN N · 2022 to 2024
$2.5MDHA brain delivery by APOE genotypeR21AG056518 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YASSINE, HUSSEIN N · 2018 to 2019
$464kNIA NIH HHS P30 AG066530NIA NIH HHS R01 AG054434NIA NIH HHS R01 AG055770NIA NIH HHS R01 AG067063NIA NIH HHS R21 AG056518NIA NIH HHS RF1 AG076124NIA NIH HHS RF1 AG078362
Abstract
Docosahexaenoic acid [22:6(
Indexed as
Alzheimer DiseaseDocosahexaenoic AcidsAnimalsApolipoprotein E4Biological TransportBrainHumansMicePositron-Emission TomographyApolipoprotein E4Docosahexaenoic Acidsdocosahexaenoic acidincorporation coefficientpolyunsaturated fatty acidpositron emission tomographyradiofluorination
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.