Evidence map›Paper›PMID 38048007›Full record

ReviewCurrent atherosclerosis reports2023

Polycystic Ovarian Syndrome: a Risk Factor for Cardiovascular Disease.

Yulith Roca Alvarez, Madison Pico, Namrita Ashokprabhu, Kareem Abou-Amro, Samantha Bailey, Elizabeth Pung, Evan Oberholster, Odayme Quesada

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross-sectional comparative echocardiographic study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Identification of crucial genes for polycystic ovary syndrome and atherosclerosis through comprehensive bioinformatics analysis and machine learning.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  8. Article
  9. Modulatory impact ofmSphere · 2025
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yulith Roca AlvarezWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Madison PicoWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Namrita AshokprabhuWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Kareem Abou-AmroWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Samantha BaileyWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Elizabeth PungWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA.
Evan OberholsterKettering Health, Kettering, OH, USA.
Odayme QuesadaWomen's Heart Center, The Christ Hospital Heart and Vascular Institute, Cincinnati, OH, USA. Odayme.Quesada@thechristhospital.com.
Christ Hospital · USChrist Hospital · USKettering University · USUniversity of Cincinnati · US

Funding

Hypertensive Disorders of Pregnancy: Pathways to Future Cardiovascular DiseaseK23HL151867 · NHLBI · THE CHRIST HOSPITAL · PI QUESADA, ODAYME · 2020 to 2024
$799k
NIH HHS K23 HL151867
6 · The paper itself

Abstract

purpose of reviewCharacterize the risk of cardiovascular disease (CVD) in individuals with polycystic ovarian syndrome (PCOS). Review the pathophysiological pathways that confers CVD risk in individuals with PCOS and interventions to reduce CVD risk. RECENT

findingsPCOS is a complex syndrome characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries that has metabolic and cardiovascular implications. Intrinsic hormonal dysregulation and chronic low-grade inflammation play an important role in the progression of atherosclerosis in young premenopausal individuals and development of CVD independently of associated traditional risk factors. Management with metformin reduces CVD risk by reducing atherosclerosis progression. PCOS is an important CVD risk factor among individuals of reproductive age. Early detection and interventions are needed to mitigate development of CVD.

Indexed as

AtherosclerosisCardiovascular DiseasesHyperandrogenismPolycystic Ovary SyndromeFemaleHumansInflammationRisk FactorsCardiovascular disease riskPCOSPolycystic ovarian syndromeSubclinical cardiovascular risk

Identifiers

PMID38048007
OpenAlexW4389311564

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.