Evidence map›Paper›PMID 38047988›Full record

ArticleJournal of fluorescence2025

Design, Synthesis, and Cellular Imaging Application of a Fluorescent Probe Based on Fluoride Ion-Induced Cyclization of Phenothiazine Derivatives.

Tingting Feng, Jiaxue Yang, San Tu, Ting Yang, Ting Wu, Wenqiang Zhu, Yi Le, Li Liu

Abstract read
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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tingting FengSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Jiaxue YangSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
San TuSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Ting YangSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Ting WuSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Wenqiang ZhuSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Yi LeSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China.
Li LiuSchool of Pharmaceutical Sciences, Guizhou University, Guiyang, 550025, China. lliu2@gzu.edu.cn.

Funding

National Natural Science Foundation of China 32260242
6 · The paper itself

Abstract

Fluoride is both necessary and potentially harmful in excessive amounts, making its detection crucial. Fluorescent probes provide a sensitive and selective means for this purpose. In this study, we developed and synthesized a fluorescent probe for LDT using phenothiazine derivatives and aryl vinyl nitrile. Initially non-fluorescent, the probe undergoes a Si-O bond breakage in the presence of fluoride ions, resulting in the formation of a larger conjugated system and subsequent fluorescence emission. The probe exhibits superior selectivity and sensitivity towards fluoride ions, with a detection limit of 0.35 µM. Moreover, cellular imaging experiments demonstrated the probe's effectiveness in recognizing fluoride ions within HepG2 cells.

Indexed as

Cell imagingFluorescent probeFluoride ionPhenothiazine

Identifiers

PMID38047988

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.