Evidence map›Paper›PMID 38047751›Full record

ArticleAntimicrobial agents and chemotherapy2024

A novel Shiga toxin 2a neutralizing antibody therapeutic with low immunogenicity and high efficacy.

Marina E Kirkland, Stephanie Patfield, Anna C Hughes, Bradley Hernlem, Xiaohua He

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. New microbes and new infections · 2026
    Review
  2. Review
  3. Repurposing of Furin Inhibitors to Reduce PathogenicAntibiotics (Basel, Switzerland) · 2025
    Article
  4. Applications of Flow Cytometry in Drug Discovery and Translational Research.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Marina E KirklandUnited States Department of Agriculture, Agricultural Research Service, Western Regional Research Center , Albany, California, USA.ORCID 0000-0002-8389-7436
Stephanie PatfieldUnited States Department of Agriculture, Agricultural Research Service, Western Regional Research Center , Albany, California, USA.
Anna C HughesUnited States Department of Agriculture, Agricultural Research Service, Western Regional Research Center , Albany, California, USA.
Bradley HernlemUnited States Department of Agriculture, Agricultural Research Service, Western Regional Research Center , Albany, California, USA.
Xiaohua HeUnited States Department of Agriculture, Agricultural Research Service, Western Regional Research Center , Albany, California, USA.ORCID 0000-0003-4606-9380
United States Department of Agriculture · USOak Ridge Associated Universities · US

Funding

U.S. Department of Agriculture (USDA) 2030-42000-053-00DU.S. Department of Energy (DOE) DE-SC0014664
6 · The paper itself

Abstract

Shiga toxin-producing

Indexed as

Escherichia coli InfectionsHemolytic-Uremic SyndromeShiga-Toxigenic Escherichia coliAdultAnimalsAntibodies, Monoclonal, HumanizedHumansMiceShiga ToxinShiga Toxin 2Antibodies, Monoclonal, HumanizedShiga ToxinShiga Toxin 2antibacterial therapeuticsexperimental therapeuticsmonoclonal antibodiesShiga toxins

Identifiers

PMID38047751
PMCPMC10777836
OpenAlexW4389311906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.