Evidence map›Paper›PMID 38047645›Full record

ArticleAntimicrobial agents and chemotherapy2024

Molnupiravir maintains antiviral activity against SARS-CoV-2 variants and exhibits a high barrier to the development of resistance.

Julie M Strizki, John M Gaspar, John A Howe, Beth Hutchins, Hiroshi Mohri, Manoj S Nair, Keith C Kinek, Philip McKenna, Shih Lin Goh, Nicholas Murgolo

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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  7. A bireporter recombinant SARS-CoV-2 Omicron BA.5 forbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Julie M StrizkiMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.ORCID 0009-0002-3893-9374
John M GasparMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
John A HoweMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Beth HutchinsMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Hiroshi MohriAaron Diamond AIDS Research Center, Columbia University Medical Center , New York, New York, USA.
Manoj S NairAaron Diamond AIDS Research Center, Columbia University Medical Center , New York, New York, USA.
Keith C KinekMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Philip McKennaMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Shih Lin GohMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Nicholas MurgoloMerck Research Laboratories (MRL), Merck & Co., Inc. , Rahway, New Jersey, USA.
Merck & Co., Inc., Rahway, NJ, USA (United States) · USAaron Diamond AIDS Research Center · US

Funding

Merck Sharp & Dohme, LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA
6 · The paper itself

Abstract

Molnupiravir, an oral prodrug of N-hydroxycytidine (NHC), previously demonstrated broad

Indexed as

COVID-19SARS-CoV-2Antiviral AgentsCytidineHumansHydroxylaminesAntiviral AgentsCytidineHydroxylaminesmolnupiravirantiviral resistanceCOVID-19molnupiravirN-hydroxycytidine

Identifiers

PMID38047645
PMCPMC10777856
OpenAlexW4389305595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.