Evidence map›Paper›PMID 38047084›Full record

ArticleiScience2023

Effects of focused ultrasound in a "clean" mouse model of ultrasonic neuromodulation.

Hongsun Guo, Hossein Salahshoor, Di Wu, Sangjin Yoo, Tomokazu Sato, Doris Y Tsao, Mikhail G Shapiro

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. In Vivo Dual-Channel Widefield GCaMP Imaging using Transparent Ultrasound Transducer.Proceedings of the ... IEEE International Symposium on Applications of Ferroelectrics. IEEE International Symposium on Applications of Ferroelectrics · 2024
    Article
  7. Article
  8. Review
  9. Article
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  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hongsun GuoDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Hossein SalahshoorDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Di WuDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Sangjin YooDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Tomokazu SatoDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Doris Y TsaoDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Mikhail G ShapiroDivision of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
California Institute of Technology · USHoward Hughes Medical Institute · US

Funding

Ultrasonic neuromodulation: establishing mechanisms and parameters to optimize targeted neuromodulation and control sensory side-effectsRF1MH117080 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ORTIZ, MICHAEL, SHAPIRO, MIKHAIL · 2018 to 2018
$3.9M
Dissecting human brain circuits in vivo using ultrasonic neuromodulationR24MH106107 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI SHAPIRO, MIKHAIL, TSAO, DORIS YING · 2014 to 2016
$1.5M
NIMH NIH HHS R24 MH106107NIMH NIH HHS RF1 MH117080
6 · The paper itself

Abstract

Recent studies on ultrasonic neuromodulation (UNM) in rodents have shown that focused ultrasound (FUS) can activate peripheral auditory pathways, leading to off-target and brain-wide excitation, which obscures the direct activation of the target area by FUS. To address this issue, we developed a new mouse model, the double transgenic Pou4f3

Indexed as

Biological sciencesNeuroscienceOptical imaging

Identifiers

PMID38047084
PMCPMC10690554
OpenAlexW4388084618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.