Evidence map›Paper›PMID 38046619›Full record

ArticleRedox biochemistry and chemistry2023

Katja E Menger, Angela Logan, Ulrich F O Luhmann, Alexander J Smith, Alan F Wright, Robin R Ali, Michael P Murphy

Abstract read
In one paragraph

Article in Redox biochemistry and chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katja E MengerUCL Institute of Ophthalmology, Bath St, London, EC1V 9EL, UK.
Angela LoganMRC-Mitochondrial Biology Unit, The Keith Peters Building, University of Cambridge, Cambridge, CB2 0XY, UK.
Ulrich F O LuhmannUCL Institute of Ophthalmology, Bath St, London, EC1V 9EL, UK.
Alexander J SmithUCL Institute of Ophthalmology, Bath St, London, EC1V 9EL, UK.
Alan F WrightMRC Human Genetics Unit, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.
Robin R AliUCL Institute of Ophthalmology, Bath St, London, EC1V 9EL, UK.
Michael P MurphyMRC-Mitochondrial Biology Unit, The Keith Peters Building, University of Cambridge, Cambridge, CB2 0XY, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a disease characterised by photoreceptor cell death. It can be initiated by mutations in a number of different genes, primarily affecting rods, which will die first, resulting in loss of night vision. The secondary death of cones then leads to loss of visual acuity and blindness. We set out to investigate whether increased mitochondrial reactive oxygen species (ROS) formation, plays a role in this sequential photoreceptor degeneration. To do this we measured mitochondrial H

Indexed as

Mitochondria: hydrogen peroxidePhotoreceptorRetinitis pigmentosa: MitoB

Identifiers

PMID38046619
PMCPMC10686909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.