Evidence map›Paper›PMID 38046544›Full record

ArticleAPL bioengineering2023

FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for

Samuel Finkel, Shannon Sweet, Tyler Locke, Sydney Smith, Zhefan Wang, Christopher Sandini, John Imredy, Yufang He, Marc Durante, Armando Lagrutta and 2 more

Open access · goldAbstract read
In one paragraph

Article in APL bioengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
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  5. Article
  6. 3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. A bioprinted model of pregnant human uterine myometrium.Frontiers in bioengineering and biotechnology · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. Advances in cardiac tissue engineering and heart-on-a-chip.Journal of biomedical materials research. Part A · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Samuel FinkelFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0005-4650-3468
Shannon SweetFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0009-3422-1059
Tyler LockeFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0007-4849-2090
Sydney SmithFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0001-1507-1720
Zhefan WangFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0009-1404-936X
Christopher SandiniFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0009-0001-6841-8767
John ImredyIn Vitro Safety Pharmacology, Genetic and Cellular Toxicology, Merck & Co. Inc., Rahway, New Jersey 07065, USA.ORCID https://orcid.org/0009-0000-8632-8012
Yufang HeDivision of Technology, Infrastructure, Operations and Experience, Merck & Co. Inc., Rahway, New Jersey 07065, USA.ORCID https://orcid.org/0009-0002-8561-2999
Marc DuranteDivision of Technology, Infrastructure, Operations and Experience, Merck & Co. Inc., Rahway, New Jersey 07065, USA.ORCID https://orcid.org/0009-0009-8501-1035
Armando LagruttaIn Vitro Safety Pharmacology, Genetic and Cellular Toxicology, Merck & Co. Inc., Rahway, New Jersey 07065, USA.
Andrew LeeFluidForm, Inc., Waltham, Massachusetts 02451, USA.ORCID https://orcid.org/0000-0001-5174-4999
Merck & Co., Inc., Rahway, NJ, USA (United States) · USCarnegie Mellon University · US

Funding

Bioprinted Human Ventricles for In Vitro Modeling of Cardiac ArrhythmiasR43HL160407 · NHLBI · FLUIDFORM, INC. · PI FEINBERG, ADAM WALTER, LEE, ANDREW · 2021 to 2021
$229k
NHLBI NIH HHS R43 HL160407
6 · The paper itself

Abstract

There is critical need for a predictive model of human cardiac physiology in drug development to assess compound effects on human tissues.

Identifiers

PMID38046544
PMCPMC10693443
OpenAlexW4389246264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.