Evidence map›Paper›PMID 38046105›Full record

ArticleCerebral circulation - cognition and behavior2023

Measurement of resistance-area product by transcranial Doppler: An alternative tool for cognitive screening in hypertensive on drug treatment?

Michel Ferreira Machado, Henrique Cotchi Simbo Muela, Valeria Aparecida Costa-Hong, Ronney B Panerai, Monica S Yassuda, Natalia Cristina Moraes, Claudia Maia Memória, Edson Bor-Seng-Shu, Ricardo Nitrini, Luiz Aparecido Bortolotto and 1 more

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Article in Cerebral circulation - cognition and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Editorial.Cerebral circulation - cognition and behavior · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michel Ferreira MachadoDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Henrique Cotchi Simbo MuelaHypertension Unit, Instituto do Coração (INCOR), University of São Paulo Medical School, Brazil.
Valeria Aparecida Costa-HongHypertension Unit, Instituto do Coração (INCOR), University of São Paulo Medical School, Brazil.
Ronney B PaneraiDepartment of Cardiovascular Sciences, University of Leicester, UK.
Monica S YassudaGerontology, School of Arts, Sciences and Humanities, University of São Paulo Medical School, Brazil.
Natalia Cristina MoraesDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Claudia Maia MemóriaDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Edson Bor-Seng-ShuDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Ricardo NitriniDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
Luiz Aparecido BortolottoHypertension Unit, Instituto do Coração (INCOR), University of São Paulo Medical School, Brazil.
Ricardo de Carvalho NogueiraDepartment of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Arterial hypertrophy and remodeling are adaptive responses present in systemic arterial hypertension that can result in silent ischemia and neurodegeneration, compromising brain connections and cognitive performance (CP). However, CP is affected differently over time, so traditional screening methods may become less sensitive in assessing certain cognitive domains. The study aimed to evaluate whether cerebrovascular hemodynamic parameters can serve as a tool for cognitive screening in hypertensive without clinically manifest cognitive decline. Methods: Participants were allocated into groups: non-hypertensive ( Results: Patients in groups 2 and 3 show no significant differences in most of the clinical-epidemiological variables or pulsatility index ( Conclusion: RAP reflects the real cerebrovascular resistance, regardless of the direct action of antihypertensive on the microcirculation, and seems to be a potential alternative tool for cognitive screening in hypertensive.

Indexed as

Arterial stiffnessCerebral blood flowCognitive declineHypertensionUltrasonography Doppler

Identifiers

PMID38046105
PMCPMC10692755

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.