Evidence map›Paper›PMID 38046060›Full record

ArticleVirusdisease2023

Co-circulation and genetic characteristics of porcine circoviruses in postweaning multisystemic wasting syndrome cases in commercial swine farms.

Danh Cong Lai, Duyen My Thi Nguyen, Toan Tat Nguyen, Tram Ngoc Thi Ngo, Duy Tien Do

Abstract read
In one paragraph

Article in Virusdisease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danh Cong LaiFaculty of Animal Science and Veterinary Medicine, Nong Lam University - HCMC (NLU), Quarter 6, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam.
Duyen My Thi NguyenFaculty of Animal Science and Veterinary Medicine, Nong Lam University - HCMC (NLU), Quarter 6, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam.
Toan Tat NguyenFaculty of Animal Science and Veterinary Medicine, Nong Lam University - HCMC (NLU), Quarter 6, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam.
Tram Ngoc Thi NgoFaculty of Animal Science and Veterinary Medicine, Nong Lam University - HCMC (NLU), Quarter 6, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam.
Duy Tien DoFaculty of Animal Science and Veterinary Medicine, Nong Lam University - HCMC (NLU), Quarter 6, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the co-infection and genetic characteristics of Porcine circoviruses in PMWS-affected pigs in five commercial farrow-to-finish swine farms in Vietnam. By the end of 2022, the percentage of PMWS-affected pigs in these farms has increased significantly compared to previous years. The lymph node samples from ten PMWS typical cases were randomly collected to test for the presence of PRRSV, PCV2, PCV3 and PCV4. While PRRSV and PCV4 were not found in these cases, 10 and 3 out of 10 samples were positive for PCV2 and PCV3, respectively. Three farms in the study showed the co-infection of PCV2 and PCV3 in affected pigs. Besides, all PCV-positive samples were sequenced to evaluate genetic characterization of PCVs in PMWS-affected cases. Phylogenetic analysis showed that all PCV3 strains in the study were clustered into PCV3b genotype. 8 out of 10 PCV2 strains belonged to PCV2d genotype while the remaining two strains belonged to PCV2b genotypes. Two farms had co-circulation of PCV2b and PCV2d genotypes in two different age groups of pigs, which is reported for the first time in Vietnam. Several amino acid substitutions were identified in important antigenic regions in the capsid protein of the PCV2 field strains compared to vaccine strains. Taken together, the results showed the high co-prevalence of PCV3 and PCV2, and the wide genetic diversity of PCV2 field and vaccine strains may be the cause of the increased PMWS situation in these pig farms. Supplementary Information: The online version contains supplementary material available at 10.1007/s13337-023-00849-4.

Indexed as

Genetic analysisMutationPCV2PCV3Porcine circovirus

Identifiers

PMID38046060
PMCPMC10686971

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.