Evidence map›Paper›PMID 38046015›Full record

ArticleClinical kidney journal2023

Risk of chronic kidney disease in patients with acute kidney injury following a major surgery: a US claims database analysis.

Christoph Ohlmeier, Johannes Schuchhardt, Chris Bauer, Meike Brinker, Sheldon X Kong, Charlie Scott, Tatsiana Vaitsiakhovich

Abstract read
In one paragraph

Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christoph OhlmeierMedical Affairs & Pharmacovigilance, Pharmaceuticals, Bayer AG, Berlin, Germany.
Johannes SchuchhardtMicroDiscovery GmbH, Berlin, Germany.
Chris BauerMicroDiscovery GmbH, Berlin, Germany.
Meike BrinkerResearch & Development, Pharmaceuticals, Bayer AG, Wuppertal, Germany.
Sheldon X KongBayer Healthcare U.S. LLC, Whippany, NJ, USA.
Charlie ScottData Science and Analytics, Bayer PLC, Reading, UK.
Tatsiana VaitsiakhovichMedical Affairs & Pharmacovigilance, Pharmaceuticals, Bayer AG, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute kidney injury (AKI) is a common complication after major surgery. This study assessed the risk of developing or worsening of chronic kidney disease (CKD) and other clinical outcomes in patients experiencing AKI after major surgery. Methods: This retrospective observational study used Optum's de-identified Clinformatics Data Mart Database to investigate cardiorenal outcomes in adult patients at the first AKI event following major surgery. The primary outcome was CKD stage ≥3; secondary outcomes included myocardial infarction (MI), stroke, heart failure, all-cause hospitalization, end-stage kidney disease, need for dialysis or kidney transplant and composite measures. Follow-up was up to 3 years. Additionally, the effect of intercurrent events on the risk of clinical outcomes was assessed. Results: Of the included patients ( Conclusion: This analysis demonstrated that patients experiencing AKI following major surgery are at high risk of developing severe CKD or worsening of pre-existing CKD and other cardiorenal clinical outcomes such as MI and stroke.

Indexed as

acute kidney injurychronic kidney diseaseend-stage kidney diseaseheart failuremajor surgery

Identifiers

PMID38046015
PMCPMC10689184

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.