Evidence map›Paper›PMID 38046001›Full record

ArticleClinical kidney journal2023

Performance of the race-free CKD-EPI creatinine-based eGFR equation in a Danish cohort with measured GFR.

Philip Vestergaard Munch, Uffe Heide-Jørgensen, Simon Kok Jensen, Henrik Birn, Søren Viborg Vestergaard, Jørgen Frøkiær, Henrik Toft Sørensen, Christian Fynbo Christiansen

Abstract read
In one paragraph

Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Parathyroid hormone and alkaline phosphatase are associated with fracture risk in non-dialysis-dependent chronic kidney disease.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Philip Vestergaard MunchDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-8239-2970
Uffe Heide-JørgensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-8407-4618
Simon Kok JensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-0032-131X
Henrik BirnDepartment of Clinical Medicine, Aarhus University, Aarhus, Midtjylland, Denmark.ORCID https://orcid.org/0000-0003-3715-7266
Søren Viborg VestergaardDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-8445-7758
Jørgen FrøkiærDepartment of Clinical Medicine, Aarhus University, Aarhus, Midtjylland, Denmark.ORCID https://orcid.org/0000-0002-6206-8065
Henrik Toft SørensenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0003-4299-7040
Christian Fynbo ChristiansenDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-0727-953X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In 2021, an updated Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for estimated glomerular filtration rate (eGFR) without a coefficient for race (CKD-EPI21) was developed. The performance of this new equation has yet to be examined among specific patient groups. Methods: We compared the performances of the new CKD-EPI21 equation and the 2009 equation assuming non-Black race (CKD-EPI09-NB) in patients with GFR measured by chromium-51-EDTA plasma clearance at Aarhus University Hospital in Denmark during 2010-18. We examined bias, accuracy, precision and correct classification of chronic kidney disease (CKD) stage using chromium-51-EDTA clearance as the reference standard. We assessed the performance in the total cohort, cancer patients and potential living kidney donors. We also assessed the performance stratified by CKD stage in the total cohort. Results: In this predominantly white population, the CKD-EPI21 equation performed slightly better than the CKD-EPI09-NB equation in both the total cohort ( Conclusions: In a selected cohort of Danish patients with mGFR, the CKD-EPI21 equation performed slightly better than the CKD-EPI09-NB equation except for patients with a mGFR <60 mL/min/1.73 m

Indexed as

CKD-EPI equationGFRrace

Identifiers

PMID38046001
PMCPMC10689151

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.