Evidence map›Paper›PMID 38045770›Full record

ArticleProceedings of the IEEE. Institute of Electrical and Electronics Engineers2020

Machine Learning in PET: from Photon Detection to Quantitative Image Reconstruction.

Kuang Gong, Eric Berg, Simon R Cherry, Jinyi Qi

Abstract read
In one paragraph

Article in Proceedings of the IEEE. Institute of Electrical and Electronics Engineers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
  2. Dynamic [Research square · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Comparison ofEJNMMI physics · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. DLSIA: Deep Learning for Scientific Image Analysis.Journal of applied crystallography · 2024
    Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Total-body PET: a new paradigm for molecular imaging.The British journal of radiology · 2022
    Review
  19. Deep Kernel Representation for Image Reconstruction in PET.IEEE transactions on medical imaging · 2022
    Article
  20. Deep learning-based time-of-flight (ToF) image enhancement of non-ToF PET scans.European journal of nuclear medicine and molecular imaging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kuang GongDepartment of Biomedical Engineering, University of California, Davis, CA, USA and is now with Massachusetts General Hospital, Boston, MA, USA.
Eric BergDepartment of Biomedical Engineering, University of California, Davis, CA, USA.
Simon R CherryDepartment of Biomedical Engineering and Department of Radiology, University of California, Davis, CA, USA.
Jinyi QiDepartment of Biomedical Engineering, University of California, Davis, CA, USA.

Funding

Optimization of PET ImagingR01EB000194 · NIBIB · UNIVERSITY OF CALIFORNIA DAVIS · PI QI, JINYI · 2003 to 2018
$3.7M
Deep learning techniques for time-of-flight PET detectorsR03EB027268 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BERG, ERIC · 2018 to 2019
$157k
NIBIB NIH HHS R01 EB000194NIBIB NIH HHS R03 EB027268
6 · The paper itself

Abstract

Machine learning has found unique applications in nuclear medicine from photon detection to quantitative image reconstruction. While there have been impressive strides in detector development for time-of-flight positron emission tomography, most detectors still make use of simple signal processing methods to extract the time and position information from the detector signals. Now with the availability of fast waveform digitizers, machine learning techniques have been applied to estimate the position and arrival time of high-energy photons. In quantitative image reconstruction, machine learning has been used to estimate various corrections factors, including scattered events and attenuation images, as well as to reduce statistical noise in reconstructed images. Here machine learning either provides a faster alternative to an existing time-consuming computation, such as in the case of scatter estimation, or creates a data-driven approach to map an implicitly defined function, such as in the case of estimating the attenuation map for PET/MR scans. In this article, we will review the abovementioned applications of machine learning in nuclear medicine.

Indexed as

attenuation correctiondeep learningdenoisingimage reconstructionmachine learningPositron emission tomographyscatter correctiontiming resolution

Identifiers

PMID38045770
PMCPMC10691821

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.