Evidence map›Paper›PMID 38045720›Full record

ArticleEvolution letters2023

Long-term evolution of antibiotic tolerance in

Melanie Ghoul, Sandra B Andersen, Rasmus L Marvig, Helle K Johansen, Lars Jelsbak, Søren Molin, Gabriel Perron, Ashleigh S Griffin

Abstract read
In one paragraph

Article in Evolution letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Surviving Colonies ofAntibiotics (Basel, Switzerland) · 2025
    Article
  6. Diversification ofMicroorganisms · 2025
    Article
  7. Review
  8. Ultrasound-Mediated Antibiotic Delivery to In Vivo Biofilm Infections: A Review.Chembiochem : a European journal of chemical biology · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Melanie GhoulDepartment of Biology, University of Oxford, Oxford, United Kingdom.
Sandra B AndersenCenter for Evolutionary Hologenomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7030-040X
Rasmus L MarvigCenter for Genomic Medicine, Rigshospitalet, Copenhagen, Denmark.
Helle K JohansenDepartment of Clinical Microbiology, Afsnit 9301, Rigshospitalet, Copenhagen Ø, Denmark.
Lars JelsbakDepartment of Biotechnology and Biomedicine, Technical University of Denmark, Lyngby, Denmark.ORCID https://orcid.org/0000-0002-5759-9769
Søren MolinDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Gabriel PerronCenter for Environmental Sciences and the Humanities, Bard College, Annandale-On-Hudson, NY, United States.ORCID https://orcid.org/0000-0003-3526-5239
Ashleigh S GriffinDepartment of Biology, University of Oxford, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic bacteria respond to antibiotic pressure with the evolution of resistance but survival can also depend on their ability to tolerate antibiotic treatment, known as tolerance. While a variety of resistance mechanisms and underlying genetics are well characterized in vitro and in vivo, an understanding of the evolution of tolerance, and how it interacts with resistance in situ is lacking. We assayed for tolerance and resistance in isolates of

Indexed as

adaptationevolutionary medicinemicrobial evolutionary genomics

Identifiers

PMID38045720
PMCPMC10693005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.