Evidence map›Paper›PMID 38045449›Full record

ArticleJournal of arrhythmia2023

Future direction of substrate-based catheter ablation in Brugada syndrome and other inherited primary arrhythmia syndromes: Systematic review and meta-analysis.

Gusti Ngurah Prana Jagannatha, I Made Putra Swi Antara, Anastasya Maria Kosasih, Bryan Gervais de Liyis, Nikita Pratama Toding Labi, Wingga Chrisna Aji, Fanny Deantri, I Made Bagus Cahya Wibawa, Ida Bagus Satriya Wibawa, Jonathan Adrian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of arrhythmia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gusti Ngurah Prana JagannathaFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.ORCID https://orcid.org/0000-0001-7371-4520
I Made Putra Swi AntaraDivision of Electrophysiology and Cardiac Pacing Department of Cardiology and Vascular Medicine, Faculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.ORCID https://orcid.org/0000-0002-1865-4163
Anastasya Maria KosasihFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.ORCID https://orcid.org/0000-0002-8018-2283
Bryan Gervais de LiyisFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.ORCID https://orcid.org/0000-0002-8272-754X
Nikita Pratama Toding LabiFaculty of Medicine Sam Ratulangi University Manado North Sulawesi Indonesia.ORCID https://orcid.org/0009-0005-5895-643X
Wingga Chrisna AjiFaculty of Medicine Muhammadiyah Yogyakarta University Yogyakarta Indonesia.
Fanny DeantriFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.
I Made Bagus Cahya WibawaFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.
Ida Bagus Satriya WibawaFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.
Jonathan AdrianFaculty of Medicine Udayana University/Prof. dr. I.G.N.G Ngoerah General Hospital Denpasar Bali Indonesia.ORCID https://orcid.org/0009-0007-7209-7680

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inherited Primary Arrhythmias Syndromes (IPAS), especially Brugada syndrome (BrS), have been associated with arrhythmogenic substrates that can be targeted through ablation. This meta-analysis evaluated the outcomes of catheter ablation (CA) in different types of IPAS based on procedural guidance and location. Methods: A systematic search was conducted across multiple databases to identify studies reporting on ventricular arrhythmia (VA) events before and after CA in IPAS, including BrS, Long-QT syndrome (LQTS), Early repolarization syndrome (ERS), and Idiopathic ventricular fibrillation (IVF). The primary outcomes were VA recurrence and VA burden, evaluated through conditional subgroup analysis. Procedural data were collected as secondary outcomes. Results: A total of 21 studies involving 584 IPAS patients who underwent CA were included. Following a mean follow-up duration of 33.5 months, substrate-based ablation demonstrated efficacy in reducing VA recurrence across all types of IPAS [RR 0.23; 95% CI (0.13-0.39); Conclusion: Substrate-based CA has demonstrated effective prevention of VA and reduction in VA burden in IPAS cases.

Indexed as

Brugada syndromecatheter ablationinherited primary arrhythmias syndromesventricular arrhythmia

Identifiers

PMID38045449
PMCPMC10692854

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.