Evidence map›Paper›PMID 38045426›Full record

ArticlebioRxiv : the preprint server for biology2023

Mechanisms of transcriptional regulation in

Naomi A Dyer, Eric R Lucas, Sanjay C Nagi, Daniel P McDermott, Jon H Brenas, Alistair Miles, Chris S Clarkson, Henry D Mawejje, Craig S Wilding, Marc S Halfon and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Naomi A DyerDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0001-8218-4605
Eric R LucasDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0003-3892-1668
Sanjay C NagiDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0003-1214-8523
Daniel P McDermottDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
Jon H BrenasWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.ORCID 0000-0001-9395-9365
Alistair MilesWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.ORCID 0000-0001-9018-4680
Chris S ClarksonWellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SA, UK.ORCID 0000-0002-8757-1660
Henry D MawejjeInfectious Diseases Research Collaboration (IDRC), Plot 2C Nakasero Hill Road, P.O.Box 7475, Kampala, Uganda.ORCID 0000-0003-4348-3682
Craig S WildingSchool of Biological and Environmental Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.ORCID 0000-0001-5818-2706
Marc S HalfonDepartment of Biochemistry, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo-State University of New York, 955 Main Street, Buffalo, New York 14203, USA.ORCID 0000-0002-4149-2705
Hasiba AsmaDepartment of Biochemistry, Jacobs School of Medicine & Biomedical Sciences, University at Buffalo-State University of New York, 955 Main Street, Buffalo, New York 14203, USA.ORCID 0000-0002-9304-2685
Eva HeinzDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0003-4413-3756
Martin J DonnellyDepartment of Vector Biology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.ORCID 0000-0001-5218-1497
Liverpool School of Tropical Medicine · GBWellcome Sanger Institute · GBJacobs (United States) · USInfectious Diseases Research Collaboration · UGLiverpool John Moores University · GB

Funding

Genome-based diagnostics for monitoring and evaluation of insecticide resistance in Anopheles gambiaeR01AI116811 · NIAID · TMLIVERPOOL SCHOOL OF TROPICAL MEDICINE · PI Martin James Donnelly · 2016 to 2026
$4.6M
Medical Research Council MR/T001070/1NIAID NIH HHS R01 AI116811Wellcome Trust
6 · The paper itself

Abstract

Malaria control relies on insecticides targeting the mosquito vector, but this is increasingly compromised by insecticide resistance, which can be achieved by elevated expression of detoxifying enzymes that metabolize the insecticide. In diploid organisms, gene expression is regulated both in

Indexed as

Allelecis-regulationinsecticideresistancetranscript

Identifiers

PMID38045426
PMCPMC10690255
OpenAlexW4388923675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.