Evidence map›Paper›PMID 38045362›Full record

ArticlebioRxiv : the preprint server for biology2023

Hippocampal place code plasticity in CA1 requires postsynaptic membrane fusion.

Mark H Plitt, Konstantin Kaganovsky, Thomas C Südhof, Lisa M Giocomo

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Mark H PlittDepartment of Neurobiology, Stanford University School of Medicine; Stanford, CA, USA.ORCID 0000-0002-7154-6292
Konstantin KaganovskyDepartment of Neurosurgery, Stanford University School of Medicine; Stanford, CA, USA.ORCID 0000-0002-1577-109X
Thomas C SüdhofDepartment of Neurosurgery, Stanford University School of Medicine; Stanford, CA, USA.
Lisa M GiocomoDepartment of Neurobiology, Stanford University School of Medicine; Stanford, CA, USA.ORCID 0000-0003-0416-2528
Howard Hughes Medical Institute · USStanford Medicine · USStanford University · USUniversity of California, Berkeley · US

Funding

Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)U19NS118284 · NINDS · STANFORD UNIVERSITY · PI GIOCOMO, LISA · 2021 to 2025
$18.1M
The Dynamics of Neural Representations for Distinct Spatial Contexts and Memory EpisodesR01MH126904 · NIMH · STANFORD UNIVERSITY · PI Lisa Giocomo · 2022 to 2026
$2.0M
Precise neuromodulation for encoding reward in the hippocampusR01MH130452 · NIMH · STANFORD UNIVERSITY · PI Lisa Giocomo · 2022 to 2026
$2.0M
NIMH NIH HHS R01 MH126904NIMH NIH HHS R01 MH130452NINDS NIH HHS U19 NS118284
6 · The paper itself

Abstract

Rapid delivery of glutamate receptors to the postsynaptic membrane via vesicle fusion is a central component of synaptic plasticity. However, it is unknown how this process supports specific neural computations during behavior. To bridge this gap, we combined conditional genetic deletion of a component of the postsynaptic membrane fusion machinery, Syntaxin3 (Stx3), in hippocampal CA1 neurons of mice with population

Identifiers

PMID38045362
PMCPMC10690209
OpenAlexW4388879879

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.