Evidence map›Paper›PMID 38045242›Full record

ArticlebioRxiv : the preprint server for biology2024

A "suicide" BCG strain provides enhanced immunogenicity and robust protection against

Alexander A Smith, Hongwei Su, Joshua Wallach, Yao Liu, Pauline Maiello, H Jacob Borish, Caylin Winchell, Andrew W Simonson, Philana Ling Lin, Mark Rodgers and 7 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Alexander A SmithDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Hongwei SuDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Joshua WallachDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Yao LiuDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Pauline MaielloDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
H Jacob BorishDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Caylin WinchellDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Andrew W SimonsonDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Philana Ling LinThe Center for Vaccine Research, University of Pittsburgh School of Medicine, Pittsburgh PA.
Mark RodgersDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Daniel FillmoreDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Jennifer SakalDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
Kan LinDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Valerie VinetteDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Dirk SchnappingerDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
Sabine EhrtDepartment of Microbiology and Immunology, Weill Cornell Medicine, New York, NY 10021, USA.
JoAnne L FlynnDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh PA.
University of Pittsburgh · USCornell University · USCenter for Veterinary Medicine · US

Funding

IMMUNE MECHANISMS OF PROTECTION AGAINST MYCOBACTERIUM TUBERCULOSIS CENTER (IMPAC-TB)75N93019C00071 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI FORTUNE, SARAH · 2019 to 2025
$57.3M
Autoimmunity and Immunopathology Training ProgramT32AI089443 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHLOMCHIK, MARK J · 2010 to 2024
$6.6M
Development of a Self Inactivating, Highly Effective TB VaccineR01AI143788 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EHRT, SABINE, FLYNN, JOANNE L. · 2019 to 2023
$3.9M
Pittsburgh HIV Mentored Training for Investigation of Co-morbidities and Cure (HIV MeTrICC)K12HL143886 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MELLORS, JOHN W, MORRIS, ALISON · 2018 to 2022
$1.7M
Ghana-SPARCO: Ghana Sickle Pan-African Research ConsortiumU01HL157004 · NHLBI · KWAME NKRUMAH UNIVERSITY/SCIENCE/TECH · PI OFORI-ACQUAH, SOLOMON FIIFI, SARFO, FRED STEPHEN · 2021 to 2025
$1.4M
NCI NIH HHS HHSN261201500003INHLBI NIH HHS K12 HL143886NHLBI NIH HHS U01 HL157004NIAID NIH HHS 75N93019C00071NIAID NIH HHS R01 AI143788NIAID NIH HHS T32 AI089443
6 · The paper itself

Abstract

Intravenous (IV) BCG delivery provides robust protection against

Identifiers

PMID38045242
PMCPMC10690263
OpenAlexW4388923563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.