Evidence map›Paper›PMID 38045035›Full record

ArticleFrontiers in microbiology2023

Ceragenins exhibit bactericidal properties that are independent of the ionic strength in the environment mimicking cystic fibrosis sputum.

Karol Skłodowski, Łukasz Suprewicz, Sylwia Joanna Chmielewska-Deptuła, Szczepan Kaliniak, Sławomir Okła, Magdalena Zakrzewska, Łukasz Minarowski, Robert Mróz, Tamara Daniluk, Paul B Savage and 2 more

Abstract read
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In one paragraph

Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Karol SkłodowskiDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Łukasz SuprewiczDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Sylwia Joanna Chmielewska-DeptułaDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Szczepan KaliniakHoly Cross Cancer Center, Kielce, Poland.
Sławomir OkłaHoly Cross Cancer Center, Kielce, Poland.
Magdalena ZakrzewskaDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Łukasz Minarowski2nd Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland.
Robert Mróz2nd Department of Lung Diseases and Tuberculosis, Medical University of Bialystok, Bialystok, Poland.
Tamara DanilukDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Paul B SavageDepartment of Chemistry and Biochemistry, Brigham Young University, Provo, UT, United States.
Krzysztof FiedorukDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Robert BuckiDepartment of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the work was to investigate the impact of sodium chloride (NaCl) on the antimicrobial efficacy of ceragenins (CSAs) and antimicrobial peptides (AMPs) against bacterial and fungal pathogens associated with cystic fibrosis (

Indexed as

antimicrobial peptidescerageninscystic fibrosissodium chloridesputum scope statement

Identifiers

PMID38045035
PMCPMC10693459

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.