Evidence map›Paper›PMID 38044566›Full record

ArticleClinical and experimental dental research2024

Assessing the osseointegration potential of a strontium releasing nanostructured titanium oxide surface: A biomechanical study in the rabbit tibia plateau model.

Sila Cagri Isler, Benjamin Bellon, Morten Foss, Benjamin Pippenger, Andreas Stavropoulos, Ole Zoffmann Andersen

Abstract read
In one paragraph

Article in Clinical and experimental dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sila Cagri IslerDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Benjamin BellonPreclinical & Translational Research, Institut Straumann AG, Basel, Switzerland.
Morten FossiNANO and Department of Physics and Astronomy, Science and Technology, Aarhus, Denmark.
Benjamin PippengerDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-7990-5555
Andreas StavropoulosDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID 0000-0001-8161-3754
Ole Zoffmann AndersenDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.

Funding

Institut Straumann AG, Basel, Switzerland (ASP 18-102_Sr-coating).
6 · The paper itself

Abstract

objectivesTo investigate the impact of a Ti-Sr-O technology, applied to either a turned surface or an SLA surface, on the mechanical robustness of osseointegration, benchmarked against the SLActive surface. MATERIAL AND

methodsTi discs (6.25-mm-diameter and 2-mm-thick) with three different surfaces were inserted on the proximal-anterior part of the tibial plateau of adult Swedish loop rabbits: (I) turned surface modified with Ti-Sr-O (turned + Ti-Sr-O), (II) SLA surface modified with Ti-Sr-O (SLA + Ti-Sr-O), and (III) SLActive surface (SLActive). Following a healing period of 2 weeks and 4 weeks, the pull-out (PO) force needed to detach the discs from the bone was assessed, as a surrogate of osseointegration.

resultsThe SLActive surface exhibited statistically significant higher median PO forces, compared with the SLA + Ti-Sr-O surfaces at both 2- and 4 weeks post-op (p > .05). In this study, no single turned + Ti-Sr-O surface disk was integrated.

conclusionsThe tested Ti-Sr-O technology failed to enhance osseointegration; however, this finding may be related to the inappropriateness of the rabbit tibia plateau model for assessing third-generation implant surface technologies, due to the limited diffusion and clearance at the disk-bone interface.

Indexed as

Dental ImplantsOsseointegrationOxidesTitaniumAnimalsRabbitsStrontiumSurface PropertiesTibiaDental ImplantsOxidesStrontiumstrontium titanium oxideTitaniumtitanium dioxideosseointegrationpreclinical in vivoSLAStrontium

Identifiers

PMID38044566
PMCPMC10860460

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.