Evidence map›Paper›PMID 38044398›Full record

ReviewImmunologic research2024

Immune cells and hypertension.

Liren Gan, Di Ye, Yongqi Feng, Heng Pan, Xiyi Lu, Jun Wan, Jing Ye

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. HMGB1 drives T-cell activation in hypertensive males and females.American journal of physiology. Renal physiology · 2025
    Article
  9. Resistant Hypertension: A Brief Review of Pathophysiology.Journal of general internal medicine · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Liren GanDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.ORCID 0000-0001-6635-9380
Di YeDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Yongqi FengDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Heng PanDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiyi LuDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Jun WanDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China. wanjun@whu.edu.cn.
Jing YeDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China. whuyejing@163.com.
Wuhan University · CN

Funding

National Natural Science Foundation of China 82070436
6 · The paper itself

Abstract

Hypertension is one of the leading causes of death due to target organ injury from cardiovascular disease. Although there are many treatments, only one-sixth of hypertensive patients effectively control their blood pressure. Therefore, further understanding the pathogenesis of hypertension is essential for the treatment of hypertension. Much research shows that immune cells play an important role in the pathogenesis of hypertension. Here, we discuss the roles of different immune cells in hypertension. Many immune cells participate in innate and adaptive immune responses, such as monocytes/macrophages, neutrophils, dendritic cells, NK cells, and B and T lymphocytes. Immune cells infiltrate the blood vessels, kidneys, and hearts and cause damage. The mechanism is that immune cells secrete cytokines such as interleukin, interferon, and tumor necrosis factor, which affect the inflammatory reaction, oxidative stress, and kidney sodium water retention, and finally aggravate or reduce the dysfunction, remodeling, and fibrosis of the blood vessel, kidney, and heart to participate in blood pressure regulation. This article reviews the research progress on immune cells and hypertension.

Indexed as

HypertensionCytokinesHumansInflammationKidneyT-LymphocytesCytokinesHypertensionImmune cellsInterleukins

Identifiers

PMID38044398
OpenAlexW4389289587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.