Evidence map›Paper›PMID 38044383›Full record

ArticleEJNMMI physics2023

16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications.

Vanessa Nadig, Matthias Hornisch, Jakob Oehm, Katrin Herweg, Volkmar Schulz, Stefan Gundacker

Abstract read
In one paragraph

Article in EJNMMI physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Current Status of Cherenkov-Based Gamma Detectors for TOF-PET and Proton Range Verification.IEEE transactions on radiation and plasma medical sciences · 2026
    Article
  2. Improving CTR with the FastIC ASIC for TOF-PET by overcoming SiPM noise with baseline correction.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  3. Timing Performance with Broadcom Metal Trench Silicon Photomultipliers.IEEE transactions on radiation and plasma medical sciences · 2025
    Article
  4. FPGA-based digitizer for BGO-based time-of-flight PET.Physics in medicine and biology · 2025
    Article
  5. Review
  6. Article
  7. Development of Whole-Body TOF-DOI PET Detector Using Dual-Ended Readout Method.IEEE transactions on instrumentation and measurement · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vanessa NadigDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Matthias HornischDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Jakob OehmDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Katrin HerwegDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Volkmar SchulzDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Stefan GundackerDepartment of Physics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Forckenbeckstraße 55, 52074, Aachen, Germany. stefan.gundacker@pmi.rwth-aachen.de.ORCID http://orcid.org/0000-0003-2087-3266

Funding

Medizinische Fakultät, RWTH Aachen University Aktenzeichen 133/22Medizinische Fakultät, RWTH Aachen University START-Programm
6 · The paper itself

Abstract

backgroundOver the past five years, ultrafast high-frequency (HF) readout concepts have advanced the timing performance of silicon photomultipliers (SiPMs). The shown impact in time-of-flight (TOF) techniques can further push the limits in light detection and ranging (LiDAR), time-of-flight positron-emission tomography (TOF-PET), time-of-flight computed tomography (TOF-CT) or high-energy physics (HEP). However, upscaling these electronics to a system-applicable, multi-channel readout, has remained a challenging task, posed by the use of discrete components and a high power consumption. To this day, there are no means to exploit the high TOF resolution of these electronics on system scale or to measure the actual timing performance limits of a full detector block.

methodsIn this work, we present a 16-channel HF readout board, including leading-edge discrimination and a linearized time-over-threshold (TOT) method, which is fully compatible with a high-precision time-to-digital converters (TDCs), such as the picoTDC developed at CERN. The discrete implementation allows ideal adaptation of this readout to a broad range of detection tasks. As a first step, the functionality of the circuit has been tested using the TOFPET2 ASIC as back-end electronics to emulate the TDC, also in view of its properties as a highly scalable data acquisition solution.

resultsThe produced board is able to mitigate influences of baseline shifts in the TOFPET2 front end, which has been shown in experiments with a pulsed laser, increasing the achievable intrinsic coincidence timing resolution (CTR) of the TOFPET2 readout electronics from 70 ps (FWHM) to 62 ps (FWHM). Single-channel coincidence experiments including a [Formula: see text]-source, 2[Formula: see text]2[Formula: see text]3 mm[Formula: see text] LYSO:Ce,Ca crystals and Broadcom NUV-MT SiPMs resulted in a CTR of 118 ps (FWHM). For a 4[Formula: see text]4 matrix of 3.88[Formula: see text]3.88[Formula: see text]19 mm[Formula: see text] LYSO:Ce,Ca crystals one-to-one coupled to a 4[Formula: see text]4 array of Broadcom NUV-MT SiPMs, an average CTR of 223 ps (FWHM) was obtained.

conclusionThe implemented 16-channel HF electronics are fully functionall and have a negligible influence on the timing performance of the back-end electronics used, here the TOFPET2 ASIC. The ongoing integration of the picoTDC with the 16-channel HF board is expected to further set the path toward sub-100 ps TOF-PET and sub-30ps TOF resolution for single-photon detection.

Indexed as

CTRFast timingHigh-frequency readoutPETTime-of-flightTOFPET2 ASICTOT discrimination

Identifiers

PMID38044383
PMCPMC10694125

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.