Evidence map›Paper›PMID 38044379›Full record

ArticleTropical animal health and production2023

Genome-wide association study for reproduction traits in Colombian Creole Blanco Orejinegro cattle.

Ana Cristina Herrera Rios, Sindy Liliana Caivio Nasner, Marisol Londoño-Gil, Luis Gabriel Gonzalez-Herrera, Albeiro Lopez-Herrera, Juan Carlos Rincón Flórez

Abstract read
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Genomic Analysis of Taurine and Indicine Ancestry in the Montana Tropical Composite Population.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  2. Candidate genes related to growth and milk production in three Anatolian goats revealed by GWAS.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  3. Signature of Selection Analysis Reveals Candidate Genes Related to Climate Adaptation and Production Traits in Lao Native Goats.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Cristina Herrera RiosGrupo de Investigación Biodiversidad y Genética Molecular (BIOGEM), Universidad Nacional de Colombia Sede Medellín, Carrera 65 N 59A-110, 050034, Medellín, Colombia. anacristinah@gmail.com.ORCID http://orcid.org/0000-0001-8667-4556
Sindy Liliana Caivio NasnerGrupo de Investigación Biomolecular y Pecuaria BIOPEC, Universidad Tecnológica de Pereira, Cra. 27 N10-02, 660003, Pereira, Risaralda, Colombia.ORCID http://orcid.org/0000-0002-8700-0278
Marisol Londoño-GilGrupo de Investigación Biodiversidad y Genética Molecular (BIOGEM), Universidad Nacional de Colombia Sede Medellín, Carrera 65 N 59A-110, 050034, Medellín, Colombia.ORCID http://orcid.org/0000-0001-6522-5567
Luis Gabriel Gonzalez-HerreraGrupo de Investigación Biodiversidad y Genética Molecular (BIOGEM), Universidad Nacional de Colombia Sede Medellín, Carrera 65 N 59A-110, 050034, Medellín, Colombia.ORCID http://orcid.org/0000-0001-7156-9753
Albeiro Lopez-HerreraGrupo de Investigación Biodiversidad y Genética Molecular (BIOGEM), Universidad Nacional de Colombia Sede Medellín, Carrera 65 N 59A-110, 050034, Medellín, Colombia.ORCID http://orcid.org/0000-0003-1444-3470
Juan Carlos Rincón FlórezGrupo de Investigación Biodiversidad y Genética Molecular (BIOGEM), Universidad Nacional de Colombia Sede Medellín, Carrera 65 N 59A-110, 050034, Medellín, Colombia.ORCID http://orcid.org/0000-0002-6769-6407

Funding

Science and Technology Postgraduate Education and Research Development Office, Office of the Higher Education Commission 2018Science and Technology Postgraduate Education and Research Development Office, Office of the Higher Education Commission Contract number P44842-015-2018Science and Technology Postgraduate Education and Research Development Office, Office of the Higher Education Commission Minciencias code 110177658049
6 · The paper itself

Abstract

The profitability of the beef cattle production system relies heavily on reproductive traits. Unfortunately, certain traits, such as age at first calving (AFC), calving interval (CI), and gestation length (GL), can pose challenges in traditional breeding programs because of their low heritability (0.01-0.12) and sex-limited characteristics. Another important aspect is the conservation of the genetic resources of animals adapted to the Colombian regions, which implies the preservation and rational use of the creole breeds in the country market. Therefore, this study aimed to identify genomic regions in the creole cattle breed Blanco Orejinegro (BON) that influence the reproductive traits in females. The dataset comprised 439 animals and 118,116 single-nucleotide polymorphisms' (SNPs) markers. The GS3 program was used to identify the SNP effects employing the BAYES Cπ methodology. The number of SNPs with effect for AFC was 25, 1527 for CI, and 23 for GL. Some of the genes found associated with reproductive and growth traits as well as immune response and environmental adaptation ECE1, EPH, EPHB2, SMARCAL1, IGFBP5, IGFBP2, FCGRT, EGFR, MUL1, PINK1, STPG1, CNGB1, TGFB1, OXTR, IL22RA1, MYOM3, OXTR, CNR2, HIVEP3, CTPS1, CXCL8, FCGRT, MREG, TMEM169, PECR, and MC1R. Our results evidenced a high contribution of the genetic architecture of the Colombian creole cattle breed Blanco Orejinegro that may impact should be included in implementing genetic improvement and conservation programs.

Indexed as

Genome-Wide Association StudyReproductionAnimalsBayes TheoremCattleColombiaFemalePhenotypePolymorphism, Single NucleotideBovineGenetic diversityQTLSNPTropical cattle

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.