Evidence map›Paper›PMID 38043496›Full record

ArticleJournal of biomechanics2024

E-cigarette aerosol exposure effect on bone biomechanical properties in murine models.

Meagan Morgan, Yasmeen M Farra, Alexandra Vergara-Anglim, Chiara Bellini, Jessica M Oakes, Sandra J Shefelbine

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomechanics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Meagan MorganDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Yasmeen M FarraDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Alexandra Vergara-AnglimDepartment of Mechanical and Industrial Engineering, Boston, MA, USA.
Chiara BelliniDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Jessica M OakesDepartment of Bioengineering, Northeastern University, Boston, MA, USA.
Sandra J ShefelbineDepartment of Mechanical and Industrial Engineering, Boston, MA, USA; Department of Bioengineering, Northeastern University, Boston, MA, USA. Electronic address: s.shefelbine@northeastern.edu.
Northeastern University · USBoston Engineering (United States) · US

Funding

Cardiopulmonary Risk Assessment from Smoke Exposure at the Wildland Urban InterfaceR01ES033792 · NIEHS · NORTHEASTERN UNIVERSITY · PI Chiara Bellini · 2022 to 2026
$3.4M
Cardiopulmonary outcomes of dual cigarette and e-cigarette use in animal models of chronic exposureR01HL168719 · NHLBI · NORTHEASTERN UNIVERSITY · PI Chiara Bellini · 2023 to 2026
$3.1M
NHLBI NIH HHS R01 HL168719NIEHS NIH HHS R01 ES033792
6 · The paper itself

Abstract

Numerous studies have shown the detrimental health effects of tobacco smoking on bone volume and strength in human and animal models. Little is known regarding the impacts of e-cigarettes, a form of smoke-less nicotine intake, despite their growing population of users. This study uses murine models to evaluate the effects of exposure to e-cigarette aerosols (JUUL) on bone structure and strength through micro-CT imaging and mechanical testing. JUUL mice had more trabecular bone in thickness and volume, yet lower ultimate stress and modulus values in the cortical bone than the control mice. These outcomes suggest that, although vaping can result in a higher bone volume, this bone is weaker than average. E-cigarettes should be examined more closely regarding adolescence and long-term consequences on skeletal health.

Indexed as

Electronic Nicotine Delivery SystemsVapingAdolescentAerosolsAnimalsDisease Models, AnimalHumansMiceNicotineAerosolsNicotineBoneE-cigarettesMechanics

Identifiers

PMID38043496
PMCPMC10836423
OpenAlexW4388923886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.