Evidence map›Paper›PMID 38043087›Full record

Trial reportEuropean journal of applied physiology2024

Exercise training reduces systemic inflammation and improves general health status in female migraineurs: a randomised controlled trail.

Zahra Pairo, Abdolhossein Parnow, Payam Sari Aslani, Payam Mohammadi, Shahla Mirzaeei, Magni Mohr

Erratum issuedAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Clinical characteristics of patients with interstitial cystitis/bladder pain syndrome combined with migraine.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Zahra PairoBio-Sciences Department, Physical Education and Sport Sciences Faculty, Razi University, University Street, Kermanshah, Iran.
Abdolhossein ParnowBio-Sciences Department, Physical Education and Sport Sciences Faculty, Razi University, University Street, Kermanshah, Iran. parnowabdolhossein@gmail.com.ORCID http://orcid.org/0000-0003-1965-2626
Payam Sari AslaniDepartment of Neurology, University of Medical Sciences, Kermanshah, Iran.
Payam MohammadiDepartment of Neurology, University of Medical Sciences, Kermanshah, Iran.
Shahla MirzaeeiDepartment of Pharmaceutics, University of Medical Sciences, Kermanshah, Iran.
Magni MohrCentre of Health Sciences, Faculty of Health, University of the Faroe Islands, Tórshavn, Faroe Islands.
Kermanshah University of Medical Sciences · IRRazi University · IRUniversity of the Faroe Islands · FO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objectives of this study were to assess the effect of 8 weeks of moderate-intensity aerobic training on permeability inflammatory indicators of matrix metalloproteinases (MMPs) and specific tissue inhibitors of MMPs in female migraineurs.

methodsFemale migraineurs (n = 28, age 32 ± 6) were randomised into two groups: migraine with exercise training (EXE + Mig, n = 13) and migraine without exercise training (NON-EXE + Mig, n = 15). Matched healthy women were also recruited as a healthy control group (CON, n = 15). The EXE-Mig group performed 8 weeks of aerobic training. Pre and post intervention, serum matrix metalloproteinases (MMP-2 and 9) and specific tissue inhibitors of MMPs (TIMP-1 and 2) were measured. In addition, body composition indices and VO

resultsExercise training reduced serum MMP-9 in female migraineurs with between-group changes and a time x group interaction (p < 0.05). In addition, exercise training reduced the serum MMP-9/TIMP-1 ratio in female migraineurs with between-group changes and time x group interaction (p < 0.05). However, no training-induced effect was observed in serum TIMP-1, TIMP-2, MMP-2 contents (p > 0.05) and MMP-2/TIMP-2 ratio (p > 0.05). Finally, exercise training reduced body fat content, WHR and BMI, and improved VO

conclusionsOur results demonstrated beneficial effects of aerobic exercise training on some circulatory inflammation factors (MMP9, MMP-9/TIMP-1) and some health indicators in female migraineurs, suggesting that such training can be employed as a non-pharmacological therapeutic method.

Indexed as

Exercise TherapyInflammationMatrix Metalloproteinase 2Migraine DisordersTissue Inhibitor of Metalloproteinase-1AdultExerciseFemaleHealth StatusHumansMatrix Metalloproteinase 9Tissue Inhibitor of Metalloproteinase-2Matrix Metalloproteinase 2Matrix Metalloproteinase 9TIMP1 protein, humanTissue Inhibitor of Metalloproteinase-1Tissue Inhibitor of Metalloproteinase-2Aerobic trainingMatrix metalloproteinases (MMP-2, 9)MigraineSpecific tissue inhibitors of MMPs (TIMP-1, 2)Women

Identifiers

PMID38043087
OpenAlexW4389286814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.