Evidence map›Paper›PMID 38042526›Full record

ArticleOpen heart2023

Impact of serum haemoglobin-to-creatinine ratio after transcatheter aortic valve implantation.

Akihiro Ikuta, Satoki Oka, Shunsuke Matsushita, Shingo Hirao, Kazushige Kadota, Tatsuhiko Komiya, Yasushi Fuku

Open access · goldAbstract read
In one paragraph

Article in Open heart, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Impaired renal blood perfusion is closely related to right heart volume overload in congestive heart failure.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Akihiro IkutaDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan ai16142@kchnet.or.jp.ORCID 0000-0001-7000-841X
Satoki OkaDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Shunsuke MatsushitaDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Shingo HiraoDepartment of Cardiovascular Surgery, Kurashiki Central Hospital, Kurashiki, Japan.
Kazushige KadotaDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Tatsuhiko KomiyaDepartment of Cardiovascular Surgery, Kurashiki Central Hospital, Kurashiki, Japan.
Yasushi FukuDepartment of Cardiovascular Medicine, Kurashiki Central Hospital, Kurashiki, Japan.
Kurashiki Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe association between a combined anaemia and renal failure index and 1-year prognosis of patients undergoing transcatheter aortic valve implantation (TAVI) is unexplored. We aimed to investigate a simple risk score in patients undergoing TAVI.

methodsA total of 469 consecutive patients undergoing TAVI between 2015 and 2021 were enrolled. After excluding patients undergoing dialysis, the remaining 458 patients were classified according to three tertiles of the serum haemoglobin-to-creatinine (Hgb/Cr) ratio 1 day before TAVI. The primary clinical outcome measure was all-cause mortality and heart failure hospitalisation 1 year after TAVI.

resultsIn the first, second and third tertiles, the 1-year cumulative incidence of all-cause mortality was 16.9% versus 7.2% versus 2.0%, respectively (p<0.01), and that of heart failure hospitalisation was 10.7% versus 3.4% versus 0.7%, respectively (p<0.01). The indexes of the area under the curve of the Hgb/Cr ratio for all-cause mortality and heart failure hospitalisation 1 year after TAVI were both 0.73. Cut-off values were 10.1 for all-cause mortality 1 year after TAVI (OR, 4.78; 95% CI 2.43 to 9.74; p<0.01) and 10.4 for heart failure hospitalisation 1 year after TAVI (OR, 5.3; 95% CI 2.21 to 14.1; p<0.01). In the multivariate analysis, the Hgb/Cr ratio was an independent predictor of all-cause mortality and heart failure hospitalisation 1 year after TAVI.

conclusionsHgb/Cr ratio calculation 1 day before TAVI may help predict midterm all-cause mortality and heart failure hospitalisation in patients with severe aortic valve stenosis undergoing TAVI. TRIAL REGISTRATION NUMBER: 4143 (The Institutional Review Board of Kurashiki Central Hospital).

Indexed as

Aortic Valve StenosisHeart FailureTranscatheter Aortic Valve ReplacementCreatinineHemoglobinsHumansTreatment OutcomeCreatinineHemoglobinsaortic valve stenosisdeath, sudden, cardiacheart failurerisk factors

Identifiers

PMID38042526
PMCPMC10693869
OpenAlexW4389266954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.